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VRTX

Vertex Pharmaceuticals Incorporated

Price Chart
Latest Quote

$513.75

-3.74 (-0.72%)
Current Price
Previous Close $517.49
Open $514.84
Day High $514.84
Day Low $509.20
Volume 35,525
Fetched: 2026-10-27T13:44:47
Stock Information
Shares Outstanding 253.46M
Total Debt $1.98B
Cash Equivalents $7.85B
Revenue $12.59B
Net Income $4.41B
Sector Healthcare
Industry Biotechnology
Market Cap $130.22B
P/E Ratio 29.32
EPS (TTM) $17.52
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$125.29B
Sales$12.59B
Income$4.41B
Book/sh$79.92
Cash/sh$30.98
Employees6K
Financial Ratios
Quick Ratio2.54
Current Ratio3.19
Debt/Eq9.77
EPS Growth TTM6.50%
Returns & Margins
ROA11.93%
ROE23.54%
Gross Margin54.96%
Operating Margin38.05%
Profit Margin35.00%
Ownership
Insider Ownership0.21%
Institutional Ownership98.31%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E25.16
PEG2.05
P/S10.35
P/B6.43
Analyst Data
Recommendationbuy
Target Price$571.46
Technical Indicators
SMA20$509.49
SMA50$522.91
SMA200$477.86
RSI53.28
ATR14.4511
Shares Float252.68M
Short Float2.01%
Short Ratio4.39
Volatility0.28
Rel Volume0.03
Performance History
Week-0.17%
Month-2.64%
Quarter+6.29%
6 Months+19.44%
YTD+13.63%
Year+21.92%
3 Years+41.97%
5 Years+177.09%
10 Years+577.41%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-10-27 $513.75 35,525
2026-10-26 $517.49 1,189,000
2026-10-23 $523.93 832,600
2026-10-22 $535.17 1,641,200
2026-10-21 $524.52 1,448,600
2026-10-20 $514.65 1,230,000
2026-10-19 $501.95 1,298,700
2026-10-16 $499.74 1,413,000
2026-10-15 $508.75 2,262,500
2026-10-14 $498.50 2,089,700
2026-10-13 $485.22 1,187,300
2026-10-12 $507.00 952,700
2026-10-09 $510.08 1,480,800
2026-10-08 $503.25 1,488,000
2026-10-07 $505.64 806,600
2026-10-06 $502.31 775,000
2026-10-05 $503.50 914,900
2026-10-02 $504.73 939,600
2026-10-01 $506.74 1,194,400
2026-09-30 $522.81 1,146,000
2026-09-29 $526.73 688,800
2026-09-28 $527.67 823,500
About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of SCD and TDT; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease, which is in single Phase 2 trial; VX-264 for treating Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. In addition, the company also operates as a clinical-stage pharmaceutical company, that focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company sells its products primarily to specialty pharmacy and distributors, wholesalers, retail pharmacies, hospitals, and clinics. Vertex Pharmaceuticals Incorporated has a strategic collaboration with AbCellera Biologics Inc. to research, develop, manufacture, and commercialize multispecific T-cell engagers (TCEs) for autoimmune diseases and other conditions. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Reconciled Cost Of Revenue $1,651,300,000 $1,530,500,000 $1,262,200,000 $1,080,300,000
Cost Of Revenue $1,651,300,000 $1,530,500,000 $1,262,200,000 $1,080,300,000
Total Revenue $12,001,300,000 $11,020,100,000 $9,869,200,000 $8,930,700,000
Operating Revenue $11,970,600,000 $11,020,100,000 $9,869,200,000 $8,930,700,000
Expenses
Interest Expense $13,300,000 $30,600,000 $44,100,000 $54,800,000
Total Expenses $7,446,900,000 $11,253,500,000 $6,088,800,000 $4,680,800,000
Other Income Expense $-388,800,000 $-85,600,000 $28,800,000 $-107,300,000
Other Non Operating Income Expenses $-7,700,000 $-86,100,000 $-22,800,000 $-164,800,000
Net Non Operating Interest Income Expense $477,600,000 $567,500,000 $570,600,000 $89,800,000
Interest Expense Non Operating $13,300,000 $30,600,000 $44,100,000 $54,800,000
Operating Expense $5,795,600,000 $9,723,000,000 $4,826,600,000 $3,600,500,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Interest Income $477,600,000 $567,500,000 $570,600,000 $89,800,000
Interest Income $490,900,000 $598,100,000 $614,700,000 $144,600,000
Normalized Income $4,277,666,859 $-535,995,000 $3,576,978,400 $3,276,862,500
Net Income From Continuing And Discontinued Operation $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Total Operating Income As Reported $4,173,300,000 $-232,900,000 $3,832,000,000 $4,307,400,000
Net Income Common Stockholders $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income Including Noncontrolling Interests $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income Continuous Operations $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Pretax Income $4,643,200,000 $248,500,000 $4,379,800,000 $4,232,400,000
Special Income Charges $-381,100,000 $500,000 $51,600,000 $57,500,000
Interest Income Non Operating $490,900,000 $598,100,000 $614,700,000 $144,600,000
Operating Income $4,554,400,000 $-233,400,000 $3,780,400,000 $4,249,900,000
Gross Profit $10,350,000,000 $9,489,600,000 $8,607,000,000 $7,850,400,000
Per Share
Diluted EPS $15.32 $-2.08 $13.89 $12.82
Basic EPS $15.46 $-2.08 $14.05 $12.97
Other
Tax Effect Of Unusual Items $-56,633,141 $105,000 $8,978,400 $12,362,500
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $5,247,400,000 $485,800,000 $4,553,600,000 $4,378,000,000
Total Unusual Items $-381,100,000 $500,000 $51,600,000 $57,500,000
Total Unusual Items Excluding Goodwill $-381,100,000 $500,000 $51,600,000 $57,500,000
Reconciled Depreciation $209,800,000 $207,200,000 $181,300,000 $148,300,000
EBITDA (Bullshit earnings) $4,866,300,000 $486,300,000 $4,605,200,000 $4,435,500,000
EBIT $4,656,500,000 $279,100,000 $4,423,900,000 $4,287,200,000
Diluted Average Shares $258,000,000 $257,900,000 $260,500,000 $259,100,000
Basic Average Shares $255,700,000 $257,900,000 $257,700,000 $256,100,000
Diluted NI Availto Com Stockholders $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Tax Provision $690,000,000 $784,100,000 $760,200,000 $910,400,000
Impairment Of Capital Assets $379,000,000 $0 $0 -
Restructuring And Mergern Acquisition $2,100,000 $-500,000 $-51,600,000 $-57,500,000
Research And Development $4,042,500,000 $8,258,700,000 $3,690,000,000 $2,655,800,000
Selling General And Administration $1,753,100,000 $1,464,300,000 $1,136,600,000 $944,700,000
Other Special Charges - $4,628,400,000 $527,100,000 $115,500,000
Fetched: 2026-10-17
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $17,153,600,000 $14,495,700,000 $15,652,500,000 $12,221,100,000
Total Assets $25,643,000,000 $22,533,200,000 $22,730,200,000 $18,150,900,000
Total Non Current Assets $14,442,000,000 $12,936,800,000 $8,586,000,000 $4,916,100,000
Other Non Current Assets $1,236,600,000 $999,300,000 $895,300,000 $409,600,000
Non Current Deferred Assets $2,897,900,000 $2,331,100,000 $1,812,100,000 $1,246,900,000
Non Current Deferred Taxes Assets $2,897,900,000 $2,331,100,000 $1,812,100,000 $1,246,900,000
Investmentin Financial Assets $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Goodwill And Other Intangible Assets $1,512,200,000 $1,913,900,000 $1,927,900,000 $1,691,600,000
Other Intangible Assets $424,200,000 $825,900,000 $839,900,000 $603,600,000
Current Assets $11,201,000,000 $9,596,400,000 $14,144,200,000 $13,234,800,000
Other Current Assets $110,900,000 $76,400,000 $84,300,000 $74,400,000
Hedging Assets Current $6,200,000 $130,100,000 $1,800,000 $47,500,000
Prepaid Assets $736,200,000 $459,200,000 $537,600,000 $431,600,000
Inventory $1,686,800,000 $1,205,400,000 $738,800,000 $460,600,000
Receivables $2,052,800,000 $1,609,400,000 $1,563,400,000 $1,442,200,000
Accounts Receivable $2,052,800,000 $1,609,400,000 $1,563,400,000 $1,442,200,000
Cash Cash Equivalents And Short Term Investments $6,608,100,000 $6,115,900,000 $11,218,300,000 $10,778,500,000
Cash And Cash Equivalents $5,084,800,000 $4,569,600,000 $10,369,100,000 $10,504,000,000
Debt
Total Debt $2,030,500,000 $1,744,300,000 $808,400,000 $899,700,000
Long Term Debt And Capital Lease Obligation $1,953,200,000 $1,657,200,000 $724,700,000 $810,300,000
Current Debt And Capital Lease Obligation $77,300,000 $87,100,000 $83,700,000 $89,400,000
Liabilities
Total Liabilities Net Minority Interest $6,977,200,000 $6,123,600,000 $5,149,800,000 $4,238,200,000
Total Non Current Liabilities Net Minority Interest $3,116,000,000 $2,559,000,000 $1,602,400,000 $1,496,100,000
Other Non Current Liabilities $267,400,000 $203,200,000 $196,300,000 $233,000,000
Tradeand Other Payables Non Current $895,400,000 $698,600,000 $681,400,000 $452,800,000
Current Liabilities $3,861,200,000 $3,564,600,000 $3,547,400,000 $2,742,100,000
Other Current Liabilities $127,700,000 $36,600,000 $50,700,000 $62,500,000
Current Deferred Liabilities $171,800,000 $206,800,000 $170,300,000 $159,600,000
Payables And Accrued Expenses $3,484,400,000 $3,234,100,000 $3,242,700,000 $2,430,600,000
Payables $893,000,000 $877,600,000 $924,500,000 $642,200,000
Other Payable $328,200,000 $303,500,000 $460,100,000 $215,000,000
Total Tax Payable $103,100,000 $161,100,000 $99,500,000 $123,300,000
Accounts Payable $461,700,000 $413,000,000 $364,900,000 $303,900,000
Equity
Common Stock Equity $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Total Equity Gross Minority Interest $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Stockholders Equity $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Gains Losses Not Affecting Retained Earnings $-15,900,000 $127,800,000 $-14,300,000 $800,000
Other Equity Adjustments $-15,900,000 $127,800,000 $-14,300,000 $800,000
Retained Earnings $13,560,000,000 $9,606,800,000 $10,142,400,000 $6,522,800,000
Other
Ordinary Shares Number $253,991,224 $256,940,382 $257,695,221 $257,011,628
Share Issued $253,991,224 $256,940,382 $257,695,221 $257,011,628
Tangible Book Value $17,153,600,000 $14,495,700,000 $15,652,500,000 $12,221,100,000
Invested Capital $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Working Capital $7,339,800,000 $6,031,800,000 $10,596,800,000 $10,492,700,000
Capital Lease Obligations $2,030,500,000 $1,744,300,000 $808,400,000 $899,700,000
Total Capitalization $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Additional Paid In Capital $5,119,200,000 $6,672,400,000 $7,449,700,000 $7,386,500,000
Capital Stock $2,500,000 $2,600,000 $2,600,000 $2,600,000
Common Stock $2,500,000 $2,600,000 $2,600,000 $2,600,000
Preferred Stock $0 $0 $0 $0
Long Term Capital Lease Obligation $1,953,200,000 $1,657,200,000 $724,700,000 $810,300,000
Current Deferred Revenue $171,800,000 $206,800,000 $170,300,000 $159,600,000
Current Capital Lease Obligation $77,300,000 $87,100,000 $83,700,000 $89,400,000
Current Accrued Expenses $2,591,400,000 $2,356,500,000 $2,318,200,000 $1,788,400,000
Investments And Advances $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Available For Sale Securities $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Goodwill $1,088,000,000 $1,088,000,000 $1,088,000,000 $1,088,000,000
Net PPE $3,083,000,000 $2,584,600,000 $1,452,900,000 $1,455,800,000
Accumulated Depreciation $-1,204,100,000 $-1,064,800,000 $-1,188,900,000 $-1,027,300,000
Gross PPE $4,287,100,000 $3,649,400,000 $2,641,800,000 $2,483,100,000
Leases $1,009,300,000 $737,600,000 $474,600,000 $410,900,000
Other Properties $1,562,700,000 $1,356,800,000 $293,600,000 $347,400,000
Machinery Furniture Equipment $1,198,200,000 $1,060,700,000 $911,900,000 $788,600,000
Buildings And Improvements $483,800,000 $461,200,000 $928,600,000 $903,100,000
Land And Improvements $33,100,000 $33,100,000 $33,100,000 $33,100,000
Properties $0 $0 $0 $0
Finished Goods $230,100,000 $184,600,000 $135,000,000 $161,800,000
Work In Process $1,196,900,000 $768,800,000 $525,100,000 $260,700,000
Raw Materials $259,800,000 $252,000,000 $78,700,000 $38,100,000
Other Short Term Investments $1,523,300,000 $1,546,300,000 $849,200,000 $274,500,000
Treasury Shares Number - - $0 $0
Fetched: 2026-10-17
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $3,193,800,000 $-978,000,000 $3,278,900,000 $3,925,200,000
Operating Activities
Operating Cash Flow $3,631,400,000 $-492,600,000 $3,537,300,000 $4,129,900,000
Cash Flow From Continuing Operating Activities $3,631,400,000 $-492,600,000 $3,537,300,000 $4,129,900,000
Operating Gains Losses - $57,700,000 $600,000 $149,100,000
Investing Activities
Capital Expenditure $-437,600,000 $-485,400,000 $-258,400,000 $-204,700,000
Investing Cash Flow $-945,400,000 $-3,770,000,000 $-3,141,700,000 $-321,100,000
Cash Flow From Continuing Investing Activities $-945,400,000 $-3,770,000,000 $-3,141,700,000 $-321,100,000
Net Other Investing Changes $-24,700,000 $-54,000,000 $-31,000,000 $-47,800,000
Financing Activities
Repurchase Of Capital Stock $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Financing Cash Flow $-2,261,300,000 $-1,494,900,000 $-562,200,000 $-67,700,000
Cash Flow From Continuing Financing Activities $-2,261,300,000 $-1,494,900,000 $-562,200,000 $-67,700,000
Net Other Financing Charges $3,700,000 $6,200,000 $1,800,000 $3,500,000
Net Common Stock Issuance $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Other
Repayment Of Debt $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Interest Paid Supplemental Data $12,400,000 $30,500,000 $43,100,000 $52,300,000
Income Tax Paid Supplemental Data $1,566,700,000 $1,082,100,000 $1,677,300,000 $1,057,800,000
End Cash Position $5,087,800,000 $4,572,200,000 $10,372,300,000 $10,512,000,000
Beginning Cash Position $4,572,200,000 $10,372,300,000 $10,512,000,000 $6,800,100,000
Effect Of Exchange Rate Changes $90,900,000 $-42,600,000 $26,900,000 $-29,200,000
Changes In Cash $424,700,000 $-5,757,500,000 $-166,600,000 $3,741,100,000
Proceeds From Stock Option Exercised $127,700,000 $114,600,000 $134,600,000 $186,300,000
Common Stock Payments $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Net Issuance Payments Of Debt $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Net Long Term Debt Issuance $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Long Term Debt Payments $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Net Investment Purchase And Sale $-483,100,000 $-3,230,600,000 $-2,852,300,000 $227,300,000
Sale Of Investment $5,913,400,000 $4,465,600,000 $934,200,000 $920,000,000
Purchase Of Investment $-6,396,500,000 $-7,696,200,000 $-3,786,500,000 $-692,700,000
Net Intangibles Purchase And Sale $0 $-187,700,000 $-58,000,000 $0
Purchase Of Intangibles $0 $-187,700,000 $-58,000,000 $0
Net PPE Purchase And Sale $-437,600,000 $-297,700,000 $-200,400,000 $-204,700,000
Purchase Of PPE $-437,600,000 $-297,700,000 $-200,400,000 $-204,700,000
Change In Working Capital $-1,199,100,000 $-514,800,000 $-265,700,000 $340,800,000
Change In Other Current Liabilities $148,500,000 $39,700,000 $208,900,000 $498,900,000
Change In Payables And Accrued Expense $-80,100,000 $262,400,000 $478,100,000 $663,300,000
Change In Accrued Expense $-116,900,000 $212,900,000 $429,400,000 $542,500,000
Change In Payable $36,800,000 $49,500,000 $48,700,000 $120,800,000
Change In Account Payable $36,800,000 $49,500,000 $48,700,000 $120,800,000
Change In Prepaid Assets $-396,000,000 $-200,300,000 $-545,700,000 $-326,400,000
Change In Inventory $-524,200,000 $-517,300,000 $-322,900,000 $-136,400,000
Change In Receivables $-347,300,000 $-99,300,000 $-84,100,000 $-358,600,000
Changes In Account Receivables $-347,300,000 $-99,300,000 $-84,100,000 $-358,600,000
Other Non Cash Items $113,400,000 $900,000 $-42,600,000 $-45,700,000
Stock Based Compensation $685,900,000 $698,500,000 $581,200,000 $491,300,000
Asset Impairment Charge $379,000,000 $0 $0 -
Deferred Tax $-510,800,000 $-348,800,000 $-536,500,000 $-275,900,000
Deferred Income Tax $-510,800,000 $-348,800,000 $-536,500,000 $-275,900,000
Depreciation Amortization Depletion $209,800,000 $207,200,000 $181,300,000 $148,300,000
Depreciation And Amortization $209,800,000 $207,200,000 $181,300,000 $148,300,000
Net Income From Continuing Operations $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Business Purchase And Sale - $0 $0 $-295,900,000
Purchase Of Business - $0 $0 $-295,900,000
Gain Loss On Investment Securities - $57,700,000 $600,000 $149,100,000
Issuance Of Debt - - $1,800,000 $0
Long Term Debt Issuance - - $1,800,000 $0
Depreciation - - - $148,300,000
Fetched: 2026-10-17