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TSHA

Taysha Gene Therapies, Inc.

Price Chart
Latest Quote

$4.12

+0.12 (+2.87%)
Current Price
Previous Close $4.01
Open $4.04
Day High $4.21
Day Low $3.97
Volume 803,315
Fetched: 2026-10-27T15:32:31
Stock Information
Shares Outstanding 325.83M
Total Debt $56.71M
Cash Equivalents $455.41M
Revenue $5.49M
Net Income $-149.63M
Sector Healthcare
Industry Biotechnology
Market Cap $1.34B
EPS (TTM) $-0.41
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$907.90M
Sales$5.49M
Income$-149.63M
Book/sh$1.19
Cash/sh$1.40
Employees99
Financial Ratios
Quick Ratio17.53
Current Ratio17.77
Debt/Eq14.64
Returns & Margins
ROA-23.82%
ROE-47.05%
Gross Margin100.00%
Operating Margin-2792.32%
Ownership
Insider Ownership9.45%
Institutional Ownership94.27%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-8.92
P/S245.04
P/B3.47
Analyst Data
Recommendationstrong_buy
Target Price$13.00
Technical Indicators
SMA20$4.17
SMA50$4.94
SMA200$5.34
RSI43.05
ATR0.2711
Shares Float232.62M
Short Float17.15%
Short Ratio14.29
Volatility1.17
Rel Volume0.19
Performance History
Week+0.36%
Month-17.33%
Quarter-26.47%
6 Months-34.52%
YTD-21.43%
Year-13.16%
3 Years+93.66%
5 Years-76.60%
10 Years-82.86%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-10-27 $4.12 803,315
2026-10-26 $4.01 1,819,600
2026-10-23 $3.96 2,592,900
2026-10-22 $4.01 3,105,100
2026-10-21 $4.12 3,511,200
2026-10-20 $4.11 10,925,700
2026-10-19 $3.94 5,816,800
2026-10-16 $3.62 2,751,800
2026-10-15 $3.73 4,685,200
2026-10-14 $3.51 4,342,700
2026-10-13 $3.58 6,115,200
2026-10-12 $4.14 4,214,100
2026-10-09 $4.49 5,382,800
2026-10-08 $4.43 3,914,600
2026-10-07 $4.43 3,912,400
2026-10-06 $4.39 4,833,700
2026-10-05 $4.49 4,974,800
2026-10-02 $4.63 2,990,200
2026-10-01 $4.74 3,847,100
2026-09-30 $4.87 3,901,500
2026-09-29 $4.99 6,570,200
2026-09-28 $4.99 6,262,500
About Taysha Gene Therapies, Inc.

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $9,773,000 $8,333,000 $15,451,000 $2,502,000
Operating Revenue $9,773,000 $8,333,000 $15,451,000 $2,502,000
Expenses
Interest Expense $63,000 $102,000 $4,998,000 $3,798,000
Total Expenses $120,271,000 $94,954,000 $86,825,000 $128,529,000
Other Income Expense $-7,658,000 $-9,515,000 $-38,766,000 $-36,438,000
Other Non Operating Income Expenses $-6,459,000 $-4,693,000 $-1,585,000 $-18,000
Net Non Operating Interest Income Expense $9,161,000 $6,838,000 $-1,426,000 $-3,549,000
Interest Expense Non Operating $63,000 $102,000 $4,998,000 $3,798,000
Operating Expense $120,271,000 $94,954,000 $86,825,000 $128,529,000
General And Administrative Expense $33,868,000 $28,953,000 $30,047,000 $37,360,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Net Interest Income $9,161,000 $6,838,000 $-1,426,000 $-3,549,000
Interest Income $9,224,000 $6,940,000 $3,572,000 $249,000
Normalized Income $-107,796,000 $-84,476,000 $-74,385,000 $-129,594,000
Net Income From Continuing And Discontinued Operation $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Total Operating Income As Reported $-110,498,000 $-91,459,000 $-72,439,000 $-162,447,000
Net Income Common Stockholders $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Net Income $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Net Income Including Noncontrolling Interests $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Net Income Continuous Operations $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Pretax Income $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Special Income Charges $0 $-4,838,000 $-2,463,000 $-36,420,000
Interest Income Non Operating $9,224,000 $6,940,000 $3,572,000 $249,000
Operating Income $-110,498,000 $-86,621,000 $-71,374,000 $-126,027,000
Per Share
Diluted EPS $-0.34 $-0.36 $-0.96 $-3.78
Basic EPS $-0.34 $-0.36 $-0.96 $-3.78
Other
Tax Effect Of Unusual Items $0 $0 $0 $0
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-106,588,000 $-83,129,000 $-68,016,000 $-124,624,000
Total Unusual Items $-1,199,000 $-4,822,000 $-37,181,000 $-36,420,000
Total Unusual Items Excluding Goodwill $-1,199,000 $-4,822,000 $-37,181,000 $-36,420,000
Reconciled Depreciation $1,145,000 $1,245,000 $1,371,000 $1,172,000
EBITDA (Bullshit earnings) $-107,787,000 $-87,951,000 $-105,197,000 $-161,044,000
EBIT $-108,932,000 $-89,196,000 $-106,568,000 $-162,216,000
Diluted Average Shares $319,711,972 $250,134,421 $116,121,482 $43,952,015
Basic Average Shares $319,711,972 $250,134,421 $116,121,482 $43,952,015
Diluted NI Availto Com Stockholders $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Impairment Of Capital Assets $0 $4,838,000 $1,065,000 $36,420,000
Gain On Sale Of Security $-1,199,000 $16,000 $-34,718,000 -
Research And Development $86,403,000 $66,001,000 $56,778,000 $91,169,000
Selling General And Administration $33,868,000 $28,953,000 $30,047,000 $37,360,000
Other Gand A $33,868,000 $28,953,000 $30,047,000 $37,360,000
Other Special Charges - - $1,398,000 -
Fetched: 2026-10-27
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $246,938,000 $71,525,000 $74,937,000 $949,000
Total Assets $343,320,000 $160,364,000 $172,731,000 $126,276,000
Total Non Current Assets $18,673,000 $18,234,000 $22,863,000 $29,859,000
Other Non Current Assets $2,498,000 $2,368,000 $2,455,000 $3,953,000
Current Assets $324,647,000 $142,130,000 $149,868,000 $96,417,000
Other Current Assets $802,000 $308,000 $292,000 $466,000
Current Deferred Assets $195,000 $135,000 $681,000 $724,000
Restricted Cash $449,000 $449,000 $449,000 $0
Prepaid Assets $3,434,000 $2,202,000 $2,506,000 $7,347,000
Cash Cash Equivalents And Short Term Investments $319,767,000 $139,036,000 $143,940,000 $87,880,000
Cash And Cash Equivalents $319,767,000 $139,036,000 $143,940,000 $87,880,000
Assets Held For Sale Current - $0 $2,000,000 $0
Cash Equivalents - $138,308,000 $142,425,000 -
Cash Financial - $728,000 $1,515,000 $87,880,000
Non Current Deferred Assets - - - -
Debt
Total Debt $70,143,000 $63,180,000 $61,107,000 $59,928,000
Long Term Debt And Capital Lease Obligation $68,278,000 $61,303,000 $59,461,000 $58,407,000
Long Term Debt $50,106,000 $43,942,000 $40,508,000 $37,967,000
Current Debt And Capital Lease Obligation $1,865,000 $1,877,000 $1,646,000 $1,521,000
Liabilities
Total Liabilities Net Minority Interest $96,382,000 $88,839,000 $97,794,000 $125,327,000
Total Non Current Liabilities Net Minority Interest $69,830,000 $62,612,000 $61,038,000 $62,537,000
Other Non Current Liabilities $1,552,000 $1,309,000 $1,577,000 $4,130,000
Current Liabilities $26,552,000 $26,227,000 $36,756,000 $62,790,000
Other Current Liabilities $777,000 $1,190,000 $1,177,000 $650,000
Current Deferred Liabilities $0 $9,773,000 $18,106,000 $33,557,000
Payables And Accrued Expenses $14,485,000 $8,145,000 $12,014,000 $23,080,000
Payables $6,275,000 $3,592,000 $6,366,000 $10,946,000
Accounts Payable $6,275,000 $3,592,000 $6,366,000 $10,946,000
Equity
Common Stock Equity $246,938,000 $71,525,000 $74,937,000 $949,000
Total Equity Gross Minority Interest $246,938,000 $71,525,000 $74,937,000 $949,000
Stockholders Equity $246,938,000 $71,525,000 $74,937,000 $949,000
Gains Losses Not Affecting Retained Earnings $-192,000 $-4,031,000 $0 -
Other Equity Adjustments $-192,000 $-4,031,000 - -
Retained Earnings $-711,300,000 $-602,305,000 $-513,007,000 $-401,441,000
Other
Ordinary Shares Number $285,051,648 $204,943,306 $186,960,193 $63,207,507
Share Issued $285,051,648 $204,943,306 $186,960,193 $63,207,507
Tangible Book Value $246,938,000 $71,525,000 $74,937,000 $949,000
Invested Capital $297,044,000 $115,467,000 $115,445,000 $38,916,000
Working Capital $298,095,000 $115,903,000 $113,112,000 $33,627,000
Capital Lease Obligations $20,037,000 $19,238,000 $20,599,000 $21,961,000
Total Capitalization $297,044,000 $115,467,000 $115,445,000 $38,916,000
Additional Paid In Capital $958,427,000 $677,859,000 $587,942,000 $402,389,000
Capital Stock $3,000 $2,000 $2,000 $1,000
Common Stock $3,000 $2,000 $2,000 $1,000
Preferred Stock $0 $0 $0 $0
Long Term Capital Lease Obligation $18,172,000 $17,361,000 $18,953,000 $20,440,000
Current Deferred Revenue $0 $9,773,000 $18,106,000 $33,557,000
Current Capital Lease Obligation $1,865,000 $1,877,000 $1,646,000 $1,521,000
Pensionand Other Post Retirement Benefit Plans Current $9,425,000 $5,242,000 $3,813,000 $3,982,000
Current Accrued Expenses $8,210,000 $4,553,000 $5,648,000 $12,134,000
Net PPE $16,175,000 $15,866,000 $20,408,000 $25,906,000
Accumulated Depreciation $-4,684,000 $-3,584,000 $-2,979,000 $-1,642,000
Gross PPE $20,859,000 $19,450,000 $23,387,000 $27,548,000
Leases $2,152,000 $2,117,000 $2,117,000 $2,091,000
Construction In Progress $4,292,000 $4,251,000 $6,823,000 $9,633,000
Other Properties $12,745,000 $11,511,000 $12,450,000 $13,811,000
Machinery Furniture Equipment $1,670,000 $1,571,000 $1,997,000 $2,013,000
Properties $0 $0 $0 $0
Treasury Shares Number - - $0 -
Fetched: 2026-10-27
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-93,828,000 $-81,599,000 $-80,387,000 $-113,259,000
Operating Activities
Operating Cash Flow $-93,090,000 $-81,225,000 $-73,018,000 $-88,390,000
Cash Flow From Continuing Operating Activities $-93,090,000 $-81,225,000 $-73,018,000 $-88,390,000
Operating Gains Losses $1,199,000 $-16,000 $36,951,000 -
Investing Activities
Capital Expenditure $-738,000 $-374,000 $-7,369,000 $-24,869,000
Investing Cash Flow $-604,000 $-363,000 $-7,352,000 $-24,930,000
Cash Flow From Continuing Investing Activities $-604,000 $-363,000 $-7,352,000 $-24,930,000
Net Other Investing Changes $134,000 $11,000 $17,000 $-61,000
Financing Activities
Issuance Of Capital Stock $264,306,000 $76,780,000 $140,790,000 $53,244,000
Financing Cash Flow $274,589,000 $76,684,000 $136,393,000 $52,097,000
Cash Flow From Continuing Financing Activities $274,589,000 $76,684,000 $136,393,000 $52,097,000
Net Other Financing Charges $-337,000 $-185,000 $-1,015,000 $-1,400,000
Net Common Stock Issuance $264,306,000 $76,780,000 $140,790,000 $53,244,000
Common Stock Issuance $264,306,000 $76,780,000 $140,790,000 $53,244,000
Net Preferred Stock Issuance - - - -
Preferred Stock Issuance - - - -
Other
Repayment Of Debt $-40,612,000 $0 $-43,000,000 $0
Issuance Of Debt $49,853,000 $0 $39,550,000 $0
Interest Paid Supplemental Data $5,399,000 $5,282,000 $4,952,000 $2,775,000
End Cash Position $322,531,000 $141,636,000 $146,540,000 $90,517,000
Beginning Cash Position $141,636,000 $146,540,000 $90,517,000 $151,740,000
Changes In Cash $180,895,000 $-4,904,000 $56,023,000 $-61,223,000
Proceeds From Stock Option Exercised $1,379,000 $89,000 $68,000 $253,000
Net Issuance Payments Of Debt $9,241,000 $0 $-3,450,000 $0
Net Long Term Debt Issuance $9,241,000 $0 $-3,450,000 $0
Long Term Debt Payments $-40,612,000 $0 $-43,000,000 $0
Long Term Debt Issuance $49,853,000 $0 $39,550,000 $0
Net PPE Purchase And Sale $-738,000 $-374,000 $-3,869,000 $-20,619,000
Purchase Of PPE $-738,000 $-374,000 $-3,869,000 $-20,619,000
Change In Working Capital $-5,371,000 $-12,467,000 $-18,012,000 $18,518,000
Change In Other Working Capital $-9,773,000 $-8,333,000 $-15,451,000 $33,557,000
Change In Payables And Accrued Expense $6,136,000 $-4,341,000 $-8,572,000 $-17,127,000
Change In Accrued Expense $6,289,000 $-1,421,000 $-6,277,000 $-9,323,000
Change In Payable $-153,000 $-2,920,000 $-2,295,000 $-7,804,000
Change In Account Payable $-153,000 $-2,920,000 $-2,295,000 $-7,804,000
Change In Prepaid Assets $-1,734,000 $207,000 $6,011,000 $2,088,000
Other Non Cash Items $5,634,000 $1,370,000 $9,268,000 $3,471,000
Stock Based Compensation $13,298,000 $13,103,000 $7,905,000 $18,043,000
Asset Impairment Charge $0 $4,838,000 $1,065,000 $36,420,000
Depreciation Amortization Depletion $1,145,000 $1,245,000 $1,371,000 $1,172,000
Depreciation And Amortization $1,145,000 $1,245,000 $1,371,000 $1,172,000
Depreciation $1,145,000 $1,245,000 $1,371,000 $1,172,000
Gain Loss On Investment Securities $1,199,000 $-16,000 $35,585,000 -
Net Income From Continuing Operations $-108,995,000 $-89,298,000 $-111,566,000 $-166,014,000
Net Intangibles Purchase And Sale - $0 $-3,500,000 $-4,250,000
Purchase Of Intangibles - $0 $-3,500,000 $-4,250,000
Fetched: 2026-10-27