S&P 500 7,387.05 â–ŧ 197.26 (-2.60%) DOW 50,877.30 â–ŧ 684.63 (-1.33%) NASDAQ 25,726.49 â–ŧ 1,104.47 (-4.12%) US Markets Closed â€ĸ 04:08 PM ET

SYRS

Syros Pharmaceuticals, Inc.

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$0.00

-0.00 (-42.86%)
Current Price
Previous Close $0.00
Open $0.00
Day High $0.00
Day Low $0.00
Volume 904
Fetched: 2026-06-05T20:08:37
Stock Information
Shares Outstanding 26.83M
Total Debt $60.23M
Cash Equivalents $58.27M
Revenue $386K
Net Income $-97.81M
Sector Healthcare
Industry Biotechnology
Market Cap $5K
EPS (TTM) $-3.07
Exchange PNK
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📊 Comprehensive Analysis
Company Data
Enterprise Value$1.96M
Sales$386K
Income$-97.81M
Book/sh$-0.41
Cash/sh$2.17
Employees68
Financial Ratios
Quick Ratio2.05
Current Ratio2.25
Returns & Margins
ROA-59.88%
ROE-776.96%
Operating Margin-28891.71%
Ownership
Insider Ownership0.15%
Institutional Ownership9.62%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-0.00
P/S0.01
P/B-0.00
Analyst Data
Recommendationnone
Target Price$8.75
Technical Indicators
SMA20$0.00
SMA50$0.00
SMA200$0.00
RSI50.00
ATR0.0001
Shares Float26.82M
Short Float3.81%
Short Ratio0.80
Volatility1.27
Rel Volume0.43
Performance History
Week+0.00%
Month-50.00%
Quarter+0.00%
6 Months-60.00%
YTD+0.00%
Year-99.23%
3 Years-99.99%
5 Years-100.00%
10 Years-100.00%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-04 $0.00 5,369
2026-06-03 $0.00 2,771
2026-06-02 $0.00 0
2026-06-01 $0.00 65,712
2026-05-29 $0.00 2,799
2026-05-28 $0.00 5,388
2026-05-27 $0.00 1,911
2026-05-26 $0.00 8,096
2026-05-22 $0.00 14,208
2026-05-21 $0.00 43,752
2026-05-20 $0.00 622
2026-05-19 $0.00 1,650
2026-05-18 $0.00 2,665
2026-05-15 $0.00 1,724
2026-05-14 $0.00 22,692
2026-05-13 $0.00 31,462
2026-05-12 $0.00 30,367
2026-05-11 $0.00 1,175
2026-05-08 $0.00 1,893
2026-05-07 $0.00 2,837
2026-05-06 $0.00 9,726
About Syros Pharmaceuticals, Inc.

Syros Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development of treatment for hematologic malignancies. The company's lead product candidates are Tamibarotene, a selective retinoic acid receptor alpha agonist, which is in Phase III clinical trial for genomically defined subset of patients with myelodysplastic syndrome and Phase II clinical trial for patients with acute myeloid leukemia; SY-2101, a novel oral form of arsenic trioxide for treating patients with acute promyelocytic leukemia; and SY-5609, a cyclin-dependent kinase 7 inhibitor, which is in a Phase I clinical trial in patients with select advanced solid tumors. The company was formerly known as LS22, Inc. and changed its name to Syros Pharmaceuticals, Inc. in August 2012. Syros Pharmaceuticals, Inc. was incorporated in 2011 and is headquartered in Cambridge, Massachusetts.

📰 Latest News
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Income Statement (Annual)
Metric 2023-12-31 2022-12-31 2021-12-31
Revenue
Total Revenue $9,936,000 $14,880,000 $23,488,000
Operating Revenue $9,936,000 $14,880,000 $23,488,000
Expenses
Interest Expense $5,127,000 $4,134,000 $3,907,000
Total Expenses $136,435,000 $141,243,000 $122,908,000
Other Income Expense $-39,764,000 $33,711,000 $16,682,000
Net Non Operating Interest Income Expense $1,689,000 $-2,002,000 $-3,820,000
Interest Expense Non Operating $5,127,000 $4,134,000 $3,907,000
Operating Expense $136,435,000 $141,243,000 $122,908,000
General And Administrative Expense $28,282,000 $29,299,000 $23,036,000
Other Non Operating Income Expenses - $-9,510,000 -
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-164,574,000 $-94,654,000 $-86,558,000
Net Interest Income $1,689,000 $-2,002,000 $-3,820,000
Interest Income $6,816,000 $2,132,000 $87,000
Normalized Income $-124,810,000 $-128,365,000 $-103,240,000
Net Income From Continuing And Discontinued Operation $-164,574,000 $-94,654,000 $-86,558,000
Total Operating Income As Reported $-128,988,000 $-135,873,000 $-99,420,000
Net Income Common Stockholders $-164,574,000 $-94,654,000 $-86,558,000
Net Income $-164,574,000 $-94,654,000 $-86,558,000
Net Income Including Noncontrolling Interests $-164,574,000 $-94,654,000 $-86,558,000
Net Income Continuous Operations $-164,574,000 $-94,654,000 $-86,558,000
Pretax Income $-164,574,000 $-94,654,000 $-86,558,000
Special Income Charges $-2,489,000 $-9,510,000 $0
Interest Income Non Operating $6,816,000 $2,132,000 $87,000
Operating Income $-126,499,000 $-126,363,000 $-99,420,000
Per Share
Diluted EPS $-5.81 $-7.49 $-13.84
Basic EPS $-5.81 $-7.49 $-13.84
Other
Tax Effect Of Unusual Items $0 $0 $0
Tax Rate For Calcs $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-117,431,000 $-121,525,000 $-96,315,000
Total Unusual Items $-39,764,000 $33,711,000 $16,682,000
Total Unusual Items Excluding Goodwill $-39,764,000 $33,711,000 $16,682,000
Reconciled Depreciation $2,252,000 $2,706,000 $3,018,000
EBITDA (Bullshit earnings) $-157,195,000 $-87,814,000 $-79,633,000
EBIT $-159,447,000 $-90,520,000 $-82,651,000
Diluted Average Shares $28,325,779 $12,631,968 $6,253,498
Basic Average Shares $28,325,779 $12,631,968 $6,253,498
Diluted NI Availto Com Stockholders $-164,574,000 $-94,654,000 $-86,558,000
Restructuring And Mergern Acquisition $2,489,000 $9,510,000 $0
Gain On Sale Of Security $-37,275,000 $43,221,000 $16,682,000
Research And Development $108,153,000 $111,944,000 $99,872,000
Selling General And Administration $28,282,000 $29,299,000 $23,036,000
Other Gand A $28,282,000 $29,299,000 $23,036,000
Fetched: 2026-02-02
Balance Sheet (Annual)
Metric 2023-12-31 2022-12-31 2021-12-31
Assets
Net Tangible Assets $16,662,000 $127,736,000 $85,218,000
Total Assets $168,174,000 $244,486,000 $182,935,000
Total Non Current Assets $23,194,000 $33,094,000 $46,350,000
Other Non Current Assets $3,711,000 $8,434,000 $6,027,000
Current Assets $144,980,000 $211,392,000 $136,585,000
Other Current Assets $5,454,000 $7,394,000 $3,237,000
Receivables $0 $1,694,000 $2,979,000
Cash Cash Equivalents And Short Term Investments $139,526,000 $202,304,000 $130,369,000
Cash And Cash Equivalents $139,526,000 $167,467,000 $92,302,000
Investmentin Financial Assets - $0 $13,038,000
Other Receivables - $1,694,000 $2,979,000
Prepaid Assets - - $3,237,000
Accounts Receivable - - $0
Debt
Total Debt $62,075,000 $63,571,000 $65,191,000
Long Term Debt And Capital Lease Obligation $53,084,000 $61,500,000 $63,180,000
Long Term Debt $34,556,000 $40,649,000 $40,257,000
Current Debt And Capital Lease Obligation $8,991,000 $2,071,000 $2,011,000
Current Debt $6,667,000 - -
Other Current Borrowings $6,667,000 - -
Liabilities
Total Liabilities Net Minority Interest $151,512,000 $116,750,000 $97,717,000
Total Non Current Liabilities Net Minority Interest $114,831,000 $85,972,000 $66,209,000
Other Non Current Liabilities $61,747,000 $24,472,000 $3,029,000
Derivative Product Liabilities $61,747,000 $24,472,000 $3,029,000
Current Liabilities $36,681,000 $30,778,000 $31,508,000
Current Deferred Liabilities $0 $4,330,000 $10,181,000
Payables And Accrued Expenses $20,697,000 $15,848,000 $12,972,000
Payables $11,544,000 $6,411,000 $3,692,000
Accounts Payable $11,544,000 $6,411,000 $3,692,000
Non Current Deferred Liabilities - - $0
Equity
Common Stock Equity $16,662,000 $127,736,000 $85,218,000
Total Equity Gross Minority Interest $16,662,000 $127,736,000 $85,218,000
Stockholders Equity $16,662,000 $127,736,000 $85,218,000
Gains Losses Not Affecting Retained Earnings $0 $102,000 $-79,000
Retained Earnings $-722,807,000 $-558,233,000 $-463,579,000
Other Equity Adjustments - $102,000 $-79,000
Other
Ordinary Shares Number $26,448,678 $20,263,116 $6,202,403
Share Issued $26,448,678 $20,263,116 $6,202,403
Tangible Book Value $16,662,000 $127,736,000 $85,218,000
Invested Capital $57,885,000 $168,385,000 $125,475,000
Working Capital $108,299,000 $180,614,000 $105,077,000
Capital Lease Obligations $20,852,000 $22,922,000 $24,934,000
Total Capitalization $51,218,000 $168,385,000 $125,475,000
Additional Paid In Capital $739,443,000 $685,847,000 $548,870,000
Capital Stock $26,000 $20,000 $6,000
Common Stock $26,000 $20,000 $6,000
Preferred Stock $0 $0 $0
Long Term Capital Lease Obligation $18,528,000 $20,851,000 $22,923,000
Current Deferred Revenue $0 $4,330,000 $10,181,000
Current Capital Lease Obligation $2,324,000 $2,071,000 $2,011,000
Pensionand Other Post Retirement Benefit Plans Current $6,993,000 $8,529,000 $6,344,000
Current Accrued Expenses $9,153,000 $9,437,000 $9,280,000
Net PPE $19,483,000 $24,660,000 $27,285,000
Accumulated Depreciation $-7,634,000 $-12,555,000 $-9,856,000
Gross PPE $27,117,000 $37,215,000 $37,141,000
Leases $11,657,000 $11,657,000 $11,657,000
Other Properties $12,185,000 $22,447,000 $22,430,000
Machinery Furniture Equipment $3,275,000 $3,111,000 $3,054,000
Properties $0 $0 $0
Other Short Term Investments $0 $34,837,000 $38,067,000
Investments And Advances - $0 $13,038,000
Non Current Deferred Revenue - - $0
Available For Sale Securities - - $13,038,000
Construction In Progress - - $0
Fetched: 2026-02-02
Cash Flow Statement (Annual)
Metric 2023-12-31 2022-12-31 2021-12-31
Free Cash Flow
Free Cash Flow $-109,979,000 $-124,306,000 $-100,785,000
Operating Activities
Operating Cash Flow $-109,707,000 $-123,065,000 $-99,540,000
Cash Flow From Continuing Operating Activities $-109,707,000 $-123,065,000 $-99,540,000
Operating Gains Losses $37,275,000 $-38,206,000 $-16,682,000
Investing Activities
Capital Expenditure $-272,000 $-1,241,000 $-1,245,000
Investing Cash Flow $37,337,000 $67,185,000 $-52,653,000
Cash Flow From Continuing Investing Activities $37,337,000 $67,185,000 $-52,653,000
Financing Activities
Repurchase Of Capital Stock $0 $-81,000 -
Issuance Of Capital Stock $43,270,000 $119,761,000 $70,337,000
Financing Cash Flow $43,462,000 $131,045,000 $70,511,000
Cash Flow From Continuing Financing Activities $43,462,000 $131,045,000 $70,511,000
Net Common Stock Issuance $43,270,000 $119,680,000 $70,337,000
Common Stock Issuance $43,270,000 $119,761,000 $70,337,000
Net Other Financing Charges - $11,438,000 $-41,000
Net Preferred Stock Issuance - - $0
Preferred Stock Issuance - - $0
Other
Repayment Of Debt $-65,000 $-291,000 $-265,000
Interest Paid Supplemental Data $4,552,000 $3,408,000 $3,191,000
Income Tax Paid Supplemental Data $0 $0 $0
End Cash Position $141,645,000 $170,553,000 $95,388,000
Beginning Cash Position $170,553,000 $95,388,000 $177,070,000
Changes In Cash $-28,908,000 $75,165,000 $-81,682,000
Proceeds From Stock Option Exercised $257,000 $218,000 $480,000
Common Stock Payments $0 $-81,000 -
Net Issuance Payments Of Debt $-65,000 $-291,000 $-265,000
Net Long Term Debt Issuance $-65,000 $-291,000 $-265,000
Long Term Debt Payments $-65,000 $-291,000 $-265,000
Net Investment Purchase And Sale $36,049,000 $68,426,000 $-51,408,000
Sale Of Investment $87,017,000 $68,426,000 $0
Purchase Of Investment $-50,968,000 $0 $-51,408,000
Net PPE Purchase And Sale $1,288,000 $-1,241,000 $-1,245,000
Sale Of PPE $1,560,000 $0 $0
Purchase Of PPE $-272,000 $-1,241,000 $-1,245,000
Change In Working Capital $5,055,000 $-5,517,000 $-10,602,000
Change In Other Working Capital $-4,330,000 $-5,851,000 $-12,641,000
Change In Other Current Liabilities $-959,000 $-848,000 -
Change In Other Current Assets $3,756,000 $-2,407,000 $-1,196,000
Change In Payables And Accrued Expense $2,954,000 $5,111,000 $4,878,000
Change In Accrued Expense $-2,179,000 $2,345,000 $4,830,000
Change In Payable $5,133,000 $2,766,000 $48,000
Change In Account Payable $5,133,000 $2,766,000 $48,000
Change In Prepaid Assets $1,940,000 $-2,807,000 $-995,000
Change In Receivables $1,694,000 $1,285,000 $-648,000
Other Non Cash Items $650,000 $953,000 $706,000
Stock Based Compensation $10,434,000 $11,410,000 $10,354,000
Asset Impairment Charge $515,000 $0 -
Amortization Of Securities $-1,314,000 $243,000 $224,000
Depreciation Amortization Depletion $2,252,000 $2,706,000 $3,018,000
Depreciation And Amortization $2,252,000 $2,706,000 $3,018,000
Gain Loss On Investment Securities $37,275,000 $-38,206,000 $-16,682,000
Net Income From Continuing Operations $-164,574,000 $-94,654,000 $-86,558,000
Issuance Of Debt - $0 $0
Long Term Debt Issuance - $0 $0
Changes In Account Receivables - $0 $7,000
Depreciation - $2,967,000 $3,018,000
Gain Loss On Sale Of PPE - - $0
Fetched: 2026-02-02