QURE
uniQure N.V.
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Latest Quote
$48.72
| Previous Close | $49.56 |
| Open | $49.19 |
| Day High | $49.51 |
| Day Low | $48.29 |
| Volume | 843,554 |
Stock Information
| Shares Outstanding | 69.37M |
| Total Debt | $552.17M |
| Cash Equivalents | $810.33M |
| Revenue | $18.67M |
| Net Income | $-252.21M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $3.38B |
| EPS (TTM) | $-4.06 |
| Exchange | NMS |
Recent Price History
About uniQure N.V.
uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in Phase I/II clinical study for the treatment of Huntington's disease. The company also develops AMT-260, which is in Phase I/IIa clinical trial for the treatment of mesial temporal lobe epilepsy; AMT-162, which is in Phase I/IIa clinical trial to treat superoxide dismutase enzyme-amyotrophic lateral sclerosis; and AMT-191, an investigational gene therapy candidate which is in phase I/IIa clinical trial for the treatment of fabry disease. It has a licensing agreement with Apic Bio to develop, manufacture, and commercialize intrathecally administered investigational gene therapy for ALS caused by mutations in SOD-1; and development and commercial supply agreement with CLS Bhering. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.
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Income Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Reconciled Cost Of Revenue | $1,686,000 | $7,796,000 | $3,779,000 | $3,343,000 |
| Cost Of Revenue | $1,686,000 | $18,327,000 | $13,628,000 | $3,343,000 |
| Total Revenue | $16,098,000 | $27,119,000 | $15,843,000 | $106,483,000 |
| Operating Revenue | $16,098,000 | $27,119,000 | $15,843,000 | $106,483,000 |
| Expenses | ||||
| Interest Expense | $61,994,000 | $63,741,000 | $41,557,000 | $11,704,000 |
| Total Expenses | $203,925,000 | $209,299,000 | $298,329,000 | $250,729,000 |
| Rent Expense Supplemental | $1,791,000 | $1,358,000 | $900,000 | $820,000 |
| Other Income Expense | $39,514,000 | $-12,621,000 | $-2,076,000 | $27,122,000 |
| Other Non Operating Income Expenses | $7,383,000 | $-2,041,000 | $766,000 | $1,087,000 |
| Net Non Operating Interest Income Expense | $-45,027,000 | $-42,326,000 | $-21,995,000 | $-11,095,000 |
| Interest Expense Non Operating | $61,994,000 | $63,741,000 | $41,557,000 | $11,704,000 |
| Operating Expense | $202,239,000 | $190,972,000 | $284,701,000 | $247,386,000 |
| Other Operating Expenses | $-5,681,000 | $-5,602,000 | $-5,293,000 | $-6,084,000 |
| General And Administrative Expense | $65,337,000 | $50,682,000 | $73,079,000 | $54,698,000 |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Net Interest Income | $-45,027,000 | $-42,326,000 | $-21,995,000 | $-11,095,000 |
| Interest Income | $16,967,000 | $21,415,000 | $19,562,000 | $609,000 |
| Normalized Income | $-222,812,202 | $-231,705,640 | $-306,369,236 | $-152,525,608 |
| Net Income From Continuing And Discontinued Operation | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Total Operating Income As Reported | $-185,349,000 | $-184,294,000 | $-282,871,000 | $-143,159,000 |
| Net Income Common Stockholders | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Net Income | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Net Income Including Noncontrolling Interests | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Net Income Continuous Operations | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Pretax Income | $-193,340,000 | $-237,127,000 | $-306,557,000 | $-128,259,000 |
| Special Income Charges | $6,000,000 | $-73,000 | $-361,000 | $0 |
| Interest Income Non Operating | $16,967,000 | $21,415,000 | $19,562,000 | $609,000 |
| Operating Income | $-187,827,000 | $-182,180,000 | $-282,486,000 | $-144,246,000 |
| Depreciation Amortization Depletion Income Statement | $1,910,000 | $2,110,000 | $2,051,000 | $1,181,000 |
| Depreciation And Amortization In Income Statement | $1,910,000 | $2,110,000 | $2,051,000 | $1,181,000 |
| Depreciation Income Statement | $1,910,000 | $2,110,000 | $2,051,000 | $1,181,000 |
| Gross Profit | $14,412,000 | $8,792,000 | $2,215,000 | $103,140,000 |
| Per Share | ||||
| Diluted EPS | $-3.46 | $-4.92 | $-6.47 | $-2.71 |
| Basic EPS | $-3.46 | $-4.92 | $-6.47 | $-2.71 |
| Other | ||||
| Tax Effect Of Unusual Items | $8,289,798 | $-2,729,640 | $-733,236 | $298,392 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-148,718,000 | $-150,165,000 | $-250,258,000 | $-134,053,000 |
| Total Unusual Items | $32,131,000 | $-10,580,000 | $-2,842,000 | $26,035,000 |
| Total Unusual Items Excluding Goodwill | $32,131,000 | $-10,580,000 | $-2,842,000 | $26,035,000 |
| Reconciled Depreciation | $14,759,000 | $12,641,000 | $11,900,000 | $8,537,000 |
| EBITDA (Bullshit earnings) | $-116,587,000 | $-160,745,000 | $-253,100,000 | $-108,018,000 |
| EBIT | $-131,346,000 | $-173,386,000 | $-265,000,000 | $-116,555,000 |
| Diluted Average Shares | $57,502,068 | $48,649,129 | $47,670,986 | $46,735,045 |
| Basic Average Shares | $57,502,068 | $48,649,129 | $47,670,986 | $46,735,045 |
| Diluted NI Availto Com Stockholders | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Tax Provision | $5,631,000 | $2,429,000 | $1,921,000 | $-1,470,000 |
| Gain On Sale Of Ppe | $6,000,000 | $0 | $0 | - |
| Gain On Sale Of Business | $0 | $1,150,000 | $0 | $0 |
| Restructuring And Mergern Acquisition | $0 | $1,223,000 | $361,000 | $0 |
| Gain On Sale Of Security | $26,131,000 | $-10,507,000 | $-2,481,000 | $26,035,000 |
| Research And Development | $140,673,000 | $143,782,000 | $214,864,000 | $197,591,000 |
| Selling General And Administration | $65,337,000 | $50,682,000 | $73,079,000 | $54,698,000 |
| Other Gand A | $28,505,000 | $16,053,000 | $30,394,000 | $17,334,000 |
| Rent And Landing Fees | $1,791,000 | $1,358,000 | $900,000 | $820,000 |
| Salaries And Wages | $35,041,000 | $33,271,000 | $41,785,000 | $36,544,000 |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $100,756,000 | $-100,209,000 | $120,810,000 | $391,650,000 |
| Total Assets | $824,908,000 | $556,536,000 | $831,689,000 | $704,964,000 |
| Total Non Current Assets | $168,922,000 | $166,247,000 | $179,836,000 | $228,190,000 |
| Other Non Current Assets | $5,561,000 | $1,399,000 | $3,184,000 | $6,061,000 |
| Non Current Deferred Assets | $8,654,000 | $9,856,000 | $12,276,000 | $14,528,000 |
| Non Current Deferred Taxes Assets | $8,654,000 | $9,856,000 | $12,276,000 | $14,528,000 |
| Goodwill And Other Intangible Assets | $98,145,000 | $93,457,000 | $86,860,000 | $84,359,000 |
| Other Intangible Assets | $72,790,000 | $71,043,000 | $60,481,000 | $58,778,000 |
| Current Assets | $655,986,000 | $390,289,000 | $651,853,000 | $476,774,000 |
| Other Current Assets | $7,076,000 | $7,606,000 | $2,655,000 | $2,814,000 |
| Prepaid Assets | $20,506,000 | $9,281,000 | $15,089,000 | $11,817,000 |
| Receivables | $5,863,000 | $5,881,000 | $4,193,000 | $102,376,000 |
| Accounts Receivable | $5,863,000 | $5,881,000 | $4,193,000 | $102,376,000 |
| Cash Cash Equivalents And Short Term Investments | $622,541,000 | $367,521,000 | $617,892,000 | $352,843,000 |
| Cash And Cash Equivalents | $80,240,000 | $158,930,000 | $241,360,000 | $228,012,000 |
| Inventory | - | $0 | $12,024,000 | $6,924,000 |
| Investmentin Financial Assets | - | - | $0 | $39,984,000 |
| Debt | ||||
| Total Debt | $63,393,000 | $66,061,000 | $138,409,000 | $142,892,000 |
| Long Term Debt And Capital Lease Obligation | $59,531,000 | $62,460,000 | $130,065,000 | $134,510,000 |
| Long Term Debt | $49,699,000 | $51,324,000 | $101,749,000 | $102,791,000 |
| Current Debt And Capital Lease Obligation | $3,862,000 | $3,601,000 | $8,344,000 | $8,382,000 |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $626,007,000 | $563,288,000 | $624,019,000 | $228,955,000 |
| Total Non Current Liabilities Net Minority Interest | $563,088,000 | $523,235,000 | $550,344,000 | $153,036,000 |
| Other Non Current Liabilities | $495,590,000 | $453,732,000 | $412,736,000 | $10,269,000 |
| Non Current Deferred Liabilities | $7,967,000 | $7,043,000 | $7,543,000 | $8,257,000 |
| Non Current Deferred Taxes Liabilities | $7,967,000 | $7,043,000 | $7,543,000 | $8,257,000 |
| Current Liabilities | $62,919,000 | $40,053,000 | $73,675,000 | $75,919,000 |
| Other Current Liabilities | $23,456,000 | $6,826,000 | $29,648,000 | $25,982,000 |
| Payables And Accrued Expenses | $25,660,000 | $17,336,000 | $19,420,000 | $24,354,000 |
| Payables | $5,170,000 | $7,227,000 | $6,586,000 | $10,984,000 |
| Accounts Payable | $5,170,000 | $7,227,000 | $6,586,000 | $10,984,000 |
| Current Deferred Liabilities | - | - | - | - |
| Equity | ||||
| Common Stock Equity | $198,901,000 | $-6,752,000 | $207,670,000 | $476,009,000 |
| Total Equity Gross Minority Interest | $198,901,000 | $-6,752,000 | $207,670,000 | $476,009,000 |
| Stockholders Equity | $198,901,000 | $-6,752,000 | $207,670,000 | $476,009,000 |
| Gains Losses Not Affecting Retained Earnings | $-58,222,000 | $-52,800,000 | $-53,553,000 | $-58,291,000 |
| Other Equity Adjustments | $-58,222,000 | $-52,800,000 | $-53,553,000 | $-58,291,000 |
| Retained Earnings | $-1,328,936,000 | $-1,129,965,000 | $-890,409,000 | $-581,931,000 |
| Other | ||||
| Ordinary Shares Number | $62,529,408 | $48,988,087 | $47,833,830 | $46,968,032 |
| Share Issued | $62,529,408 | $48,988,087 | $47,833,830 | $46,968,032 |
| Tangible Book Value | $100,756,000 | $-100,209,000 | $120,810,000 | $391,650,000 |
| Invested Capital | $248,600,000 | $44,572,000 | $309,419,000 | $578,800,000 |
| Working Capital | $593,067,000 | $350,236,000 | $578,178,000 | $400,855,000 |
| Capital Lease Obligations | $13,694,000 | $14,737,000 | $36,660,000 | $40,101,000 |
| Total Capitalization | $248,600,000 | $44,572,000 | $309,419,000 | $578,800,000 |
| Additional Paid In Capital | $1,582,371,000 | $1,173,068,000 | $1,148,749,000 | $1,113,393,000 |
| Capital Stock | $3,688,000 | $2,945,000 | $2,883,000 | $2,838,000 |
| Common Stock | $3,688,000 | $2,945,000 | $2,883,000 | $2,838,000 |
| Long Term Capital Lease Obligation | $9,832,000 | $11,136,000 | $28,316,000 | $31,719,000 |
| Current Capital Lease Obligation | $3,862,000 | $3,601,000 | $8,344,000 | $8,382,000 |
| Pensionand Other Post Retirement Benefit Plans Current | $9,941,000 | $12,290,000 | $16,263,000 | $17,201,000 |
| Current Accrued Expenses | $20,490,000 | $10,109,000 | $12,834,000 | $13,370,000 |
| Investments And Advances | $30,237,000 | $27,464,000 | $2,179,000 | $39,984,000 |
| Other Investments | $30,237,000 | $27,464,000 | $2,179,000 | - |
| Goodwill | $25,355,000 | $22,414,000 | $26,379,000 | $25,581,000 |
| Net PPE | $26,325,000 | $34,071,000 | $75,337,000 | $83,258,000 |
| Accumulated Depreciation | $-43,736,000 | $-31,656,000 | $-55,672,000 | $-44,126,000 |
| Gross PPE | $70,061,000 | $65,727,000 | $131,009,000 | $127,384,000 |
| Leases | $28,188,000 | $24,808,000 | $46,512,000 | $44,871,000 |
| Other Properties | $37,515,000 | $37,006,000 | $72,446,000 | $72,119,000 |
| Machinery Furniture Equipment | $4,358,000 | $3,913,000 | $6,383,000 | $4,985,000 |
| Properties | $0 | $0 | $0 | $0 |
| Other Short Term Investments | $542,301,000 | $208,591,000 | $376,532,000 | $124,831,000 |
| Construction In Progress | - | $0 | $5,668,000 | $5,409,000 |
| Finished Goods | - | $0 | $758,000 | $1,466,000 |
| Work In Process | - | $0 | $4,109,000 | $1,874,000 |
| Raw Materials | - | $0 | $7,157,000 | $3,584,000 |
| Held To Maturity Securities | - | - | $0 | $39,984,000 |
| Current Deferred Revenue | - | - | - | - |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-178,402,000 | $-194,417,000 | $-153,083,000 | $-162,748,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-177,963,000 | $-182,728,000 | $-145,929,000 | $-145,060,000 |
| Cash Flow From Continuing Operating Activities | $-177,963,000 | $-182,728,000 | $-145,929,000 | $-145,060,000 |
| Operating Gains Losses | $-35,424,000 | $15,415,000 | $-2,206,000 | $-22,083,000 |
| Investing Activities | ||||
| Capital Expenditure | $-439,000 | $-11,689,000 | $-7,154,000 | $-17,688,000 |
| Investing Cash Flow | $-321,619,000 | $162,968,000 | $-205,686,000 | $-182,734,000 |
| Cash Flow From Continuing Investing Activities | $-321,619,000 | $162,968,000 | $-205,686,000 | $-182,734,000 |
| Financing Activities | ||||
| Issuance Of Capital Stock | $391,899,000 | $2,123,000 | $308,000 | $1,445,000 |
| Financing Cash Flow | $415,398,000 | $-59,486,000 | $362,721,000 | $1,445,000 |
| Cash Flow From Continuing Financing Activities | $415,398,000 | $-59,486,000 | $362,721,000 | $1,445,000 |
| Net Common Stock Issuance | $391,899,000 | $2,123,000 | $308,000 | $1,445,000 |
| Common Stock Issuance | $391,899,000 | $2,123,000 | $308,000 | $1,445,000 |
| Net Other Financing Charges | - | $-8,559,000 | $362,413,000 | - |
| Other | ||||
| Repayment Of Debt | $0 | $-53,050,000 | $0 | $0 |
| Interest Paid Supplemental Data | $25,069,000 | $20,567,000 | $16,878,000 | $9,247,000 |
| End Cash Position | $81,802,000 | $160,329,000 | $244,544,000 | $231,173,000 |
| Beginning Cash Position | $160,329,000 | $244,544,000 | $231,173,000 | $559,353,000 |
| Effect Of Exchange Rate Changes | $5,657,000 | $-4,969,000 | $2,265,000 | $-1,831,000 |
| Changes In Cash | $-84,184,000 | $-79,246,000 | $11,106,000 | $-326,349,000 |
| Proceeds From Stock Option Exercised | $23,499,000 | $0 | $0 | - |
| Net Issuance Payments Of Debt | $0 | $-53,050,000 | $0 | $0 |
| Net Long Term Debt Issuance | $0 | $-53,050,000 | $0 | $0 |
| Long Term Debt Payments | $0 | $-53,050,000 | $0 | $0 |
| Net Investment Purchase And Sale | $-321,180,000 | $174,657,000 | $-198,532,000 | $-163,146,000 |
| Sale Of Investment | $337,195,000 | $534,498,000 | $167,907,000 | $0 |
| Purchase Of Investment | $-658,375,000 | $-359,841,000 | $-366,439,000 | $-163,146,000 |
| Net PPE Purchase And Sale | $-439,000 | $-11,689,000 | $-7,154,000 | $-17,688,000 |
| Purchase Of PPE | $-439,000 | $-11,689,000 | $-7,154,000 | $-17,688,000 |
| Change In Working Capital | $-6,790,000 | $-3,944,000 | $82,440,000 | $-43,384,000 |
| Change In Payables And Accrued Expense | $1,807,000 | $-4,122,000 | $-9,497,000 | $12,623,000 |
| Change In Accrued Expense | $4,474,000 | $-5,642,000 | $-5,328,000 | $3,385,000 |
| Change In Payable | $-2,667,000 | $1,520,000 | $-4,169,000 | $9,238,000 |
| Change In Account Payable | $-2,667,000 | $1,520,000 | $-4,169,000 | $9,238,000 |
| Change In Inventory | $0 | $2,421,000 | $-6,740,000 | $-6,924,000 |
| Change In Receivables | $-8,597,000 | $-2,243,000 | $98,677,000 | $-49,083,000 |
| Changes In Account Receivables | $-8,597,000 | $-2,243,000 | $-1,323,000 | $-4,083,000 |
| Other Non Cash Items | $39,659,000 | $18,930,000 | $44,318,000 | $5,925,000 |
| Stock Based Compensation | $17,679,000 | $22,258,000 | $35,093,000 | $34,204,000 |
| Amortization Of Securities | $-10,463,000 | $-10,901,000 | $-10,917,000 | $0 |
| Deferred Tax | $1,588,000 | $2,429,000 | $1,921,000 | $-1,470,000 |
| Deferred Income Tax | $1,588,000 | $2,429,000 | $1,921,000 | $-1,470,000 |
| Depreciation Amortization Depletion | $14,759,000 | $12,641,000 | $11,900,000 | $8,537,000 |
| Depreciation And Amortization | $14,759,000 | $12,641,000 | $11,900,000 | $8,537,000 |
| Depreciation | $14,759,000 | $12,641,000 | $11,900,000 | $8,537,000 |
| Gain Loss On Investment Securities | $-12,405,000 | - | - | - |
| Net Foreign Currency Exchange Gain Loss | $-23,019,000 | $15,415,000 | $-2,206,000 | $-22,083,000 |
| Net Income From Continuing Operations | $-198,971,000 | $-239,556,000 | $-308,478,000 | $-126,789,000 |
| Net Business Purchase And Sale | - | $0 | $0 | $-1,900,000 |
| Purchase Of Business | - | $0 | $0 | $-1,900,000 |
| Issuance Of Debt | - | - | $0 | $0 |
| Long Term Debt Issuance | - | - | $0 | $0 |
| Net Intangibles Purchase And Sale | - | - | - | $0 |
| Purchase Of Intangibles | - | - | - | $0 |