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PRQR

ProQR Therapeutics N.V.

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Latest Quote

$2.29

-0.03 (-1.29%)
Current Price
Previous Close $2.32
Open $2.31
Day High $2.35
Day Low $2.27
Volume 458,209
Fetched: 2026-08-28T22:15:10
Stock Information
Note: Financial values converted from EUR to USD
Shares Outstanding 141.12M
Total Debt $17.74M
Cash Equivalents $135.72M
Revenue $21.35M
Net Income $-48.71M
Sector Healthcare
Industry Biotechnology
Market Cap $323.16M
EPS (TTM) $-0.47
Exchange NCM
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Recent Price History
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About ProQR Therapeutics N.V.

ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs. Its lead product candidate, AX-0810, targets na-taurocholate cotransporting polypeptide (NTCP) for the treatment of cholestatic diseases. The company also develops AX-2402, which targets methyl CpG binding protein 2 mutations for Rett syndrome; AX-2911, which targets PNPLA3 for metabolic dysfunction-associated steatohepatitis; and AX-1412, which targets the B4GALT1 gene for cardiovascular diseases. It has a research and collaboration agreement with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $18,566,592 $22,067,234 $7,603,595 $4,195,167
Operating Revenue $18,566,592 $22,067,234 $7,603,595 $4,195,167
Expenses
Interest Expense $1,084,394 $1,257,149 $1,404,225 $5,984,592
Total Expenses $69,279,791 $57,636,276 $48,212,908 $80,253,294
Other Income Expense $-143,574 $394,537 $6,521,536 $7,087,662
Other Non Operating Income Expenses $274,308 $402,708 $1,112,408 $3,166,803
Net Non Operating Interest Income Expense $1,638,847 $2,537,644 $1,622,505 $-5,860,861
Interest Expense Non Operating $1,084,394 $1,257,149 $1,404,225 $5,984,592
Operating Expense $69,279,791 $57,636,276 $48,212,908 $80,253,294
Other Operating Expenses $-514,766 $-747,053 $-93,382 $-892,961
General And Administrative Expense $17,579,082 $15,946,071 $18,951,791 $21,770,747
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-49,240,105 $-32,406,909 $-32,822,457 $-75,200,183
Net Interest Income $1,638,847 $2,537,644 $1,622,505 $-5,860,861
Interest Income $2,723,240 $3,794,794 $3,026,730 $123,731
Normalized Income $-48,909,978 $-32,398,795 $-38,215,357 $-78,305,039
Net Income From Continuing And Discontinued Operation $-49,240,105 $-32,406,909 $-32,822,457 $-75,200,183
Total Operating Income As Reported $-50,713,199 $-35,569,042 $-37,188,045 $-76,058,126
Net Income Common Stockholders $-49,240,105 $-32,406,909 $-32,822,457 $-75,200,183
Net Income $-49,240,105 $-32,406,909 $-32,822,457 $-75,200,183
Net Income Including Noncontrolling Interests $-49,240,105 $-32,406,909 $-32,374,225 $-74,943,384
Net Income Continuous Operations $-49,240,105 $-32,406,909 $-32,374,225 $-74,943,384
Pretax Income $-49,217,927 $-32,636,861 $-32,465,272 $-74,831,326
Special Income Charges $0 $0 $5,706,782 $-1,622,505
Interest Income Non Operating $2,723,240 $3,794,794 $3,026,730 $123,731
Operating Income $-50,713,199 $-35,569,042 $-40,609,313 $-76,058,126
Earnings From Equity Interest - $0 $0 $-9,338
Per Share
Diluted EPS $-0.47 $-0.37 $-0.41 $-1.05
Basic EPS $-0.47 $-0.37 $-0.41 $-1.05
Other
Tax Effect Of Unusual Items $-87,755 $-57 $16,227 $825,341
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-44,560,521 $-28,148,709 $-33,536,826 $-69,834,244
Total Unusual Items $-417,883 $-8,171 $5,409,128 $3,930,197
Total Unusual Items Excluding Goodwill $-417,883 $-8,171 $5,409,128 $3,930,197
Reconciled Depreciation $3,155,130 $3,222,832 $2,933,349 $2,942,687
EBITDA (Bullshit earnings) $-44,978,403 $-28,156,880 $-28,127,698 $-65,904,047
EBIT $-48,133,533 $-31,379,711 $-31,061,047 $-68,846,734
Diluted Average Shares $122,953,603 $100,486,147 $94,562,197 $83,624,725
Basic Average Shares $122,953,603 $100,486,147 $94,562,197 $83,624,725
Diluted NI Availto Com Stockholders $-49,240,105 $-32,406,909 $-32,822,457 $-75,200,183
Minority Interests $0 $0 $-448,232 $-256,799
Tax Provision $22,178 $-229,952 $-91,047 $112,058
Gain On Sale Of Ppe $0 $0 $3,421,267 $0
Gain On Sale Of Business $0 $0 $107,389 $0
Gain On Sale Of Security $-417,883 $-8,171 $-297,654 $5,552,702
Research And Development $52,215,475 $42,437,257 $29,354,498 $59,375,508
Selling General And Administration $17,579,082 $15,946,071 $18,951,791 $21,770,747
Other Gand A $17,579,082 $15,946,071 $18,951,791 $21,770,747
Other Special Charges - - $-2,178,125 $1,622,505
Fetched: 2026-08-25
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $57,632,774 $103,373,405 $48,313,293 $78,282,942
Total Assets $131,616,662 $196,052,284 $160,946,648 $199,977,812
Total Non Current Assets $14,742,616 $16,473,677 $19,723,356 $19,681,334
Investmentin Financial Assets $0 $0 $0 $724,874
Current Assets $116,874,046 $179,578,607 $141,223,292 $180,296,478
Prepaid Assets $3,066,418 $2,813,120 $925,645 $2,858,643
Receivables $5,936,734 $2,366,056 $1,480,098 $66,809,849
Other Receivables $951,325 $1,560,640 $869,616 $66,101,316
Taxes Receivable $1,065,717 $805,416 $610,482 $708,533
Accounts Receivable $3,919,692 $0 - -
Cash Cash Equivalents And Short Term Investments $107,870,895 $174,399,431 $138,817,549 $110,627,986
Cash And Cash Equivalents $107,870,895 $174,399,431 $138,817,549 $110,627,986
Cash Equivalents $63,800,627 $87,789,187 $69,044,003 $0
Cash Financial $44,070,268 $86,610,244 $69,773,546 $110,627,986
Debt
Total Debt $18,634,293 $20,095,715 $23,034,900 $25,646,083
Long Term Debt And Capital Lease Obligation $11,143,924 $12,918,174 $21,150,927 $21,108,905
Current Debt And Capital Lease Obligation $7,490,370 $7,177,541 $1,883,973 $4,537,177
Current Debt $5,686,938 $5,348,430 - $2,918,174
Other Current Borrowings $5,686,938 $5,348,430 - $2,918,174
Long Term Debt - - $5,009,922 $4,985,409
Liabilities
Total Liabilities Net Minority Interest $73,983,888 $92,678,880 $112,633,355 $122,143,101
Total Non Current Liabilities Net Minority Interest $36,116,492 $47,269,754 $72,709,230 $97,644,445
Non Current Deferred Liabilities $24,972,568 $34,351,580 $51,558,303 $76,535,540
Current Liabilities $37,867,396 $45,409,126 $39,924,126 $24,498,656
Other Current Liabilities $9,541,263 $10,875,452 $10,295,319 $11,614,334
Current Deferred Liabilities $20,487,918 $25,612,232 $24,009,570 $6,584,568
Payables And Accrued Expenses $347,846 $1,743,901 $3,735,263 $1,762,577
Payables $347,846 $1,743,901 $3,735,263 $1,762,577
Total Tax Payable $0 $1,725,225 $1,936,500 $1,305,008
Accounts Payable $347,846 $18,676 $1,798,763 $457,570
Equity
Common Stock Equity $57,632,774 $103,373,405 $48,313,293 $78,282,942
Total Equity Gross Minority Interest $57,632,774 $103,373,405 $48,313,293 $77,834,711
Stockholders Equity $57,632,774 $103,373,405 $48,313,293 $78,282,942
Gains Losses Not Affecting Retained Earnings $33,490,135 $32,214,309 $30,320,998 $35,326,250
Retained Earnings $-545,705,588 $-498,608,591 $-467,900,059 $-442,522,449
Long Term Equity Investment - - - $0
Other
Treasury Shares Number $2,742,911 $2,916,294 $3,377,836 $4,003,604
Ordinary Shares Number $122,984,778 $122,811,395 $94,962,750 $94,335,328
Share Issued $125,727,689 $125,727,689 $98,340,586 $98,338,932
Tangible Book Value $57,632,774 $103,373,405 $48,313,293 $78,282,942
Invested Capital $63,319,712 $108,721,834 $53,323,214 $86,186,526
Working Capital $79,006,650 $134,169,481 $101,299,166 $155,797,821
Capital Lease Obligations $12,947,356 $14,747,285 $18,024,979 $17,742,499
Total Capitalization $57,632,774 $103,373,405 $53,323,214 $83,268,351
Minority Interest $0 $0 $0 $-448,232
Additional Paid In Capital $564,819,630 $564,739,088 $481,958,656 $481,545,442
Capital Stock $5,028,598 $5,028,598 $3,933,699 $3,933,699
Common Stock $5,028,598 $5,028,598 $3,933,699 $3,933,699
Non Current Deferred Revenue $24,972,568 $34,351,580 $51,558,303 $76,535,540
Long Term Capital Lease Obligation $11,143,924 $12,918,174 $16,141,005 $16,123,496
Current Deferred Revenue $20,487,918 $25,612,232 $24,009,570 $6,584,568
Current Capital Lease Obligation $1,803,432 $1,829,112 $1,883,973 $1,619,003
Investments And Advances $0 $0 $0 $724,874
Net PPE $14,742,616 $16,473,677 $19,723,356 $18,956,460
Accumulated Depreciation $-24,114,625 $-20,959,495 $-17,736,663 $-15,027,430
Gross PPE $38,857,241 $37,433,172 $37,460,019 $33,983,890
Other Properties $10,619,820 $9,660,324 $8,540,912 $7,296,603
Properties $28,237,421 $27,772,848 $28,919,107 $26,687,287
Investmentsin Associatesat Cost - - - $0
Pensionand Other Post Retirement Benefit Plans Current - - - -
Fetched: 2026-08-25
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-62,811,950 $-44,135,635 $23,552,001 $-80,793,740
Operating Activities
Operating Cash Flow $-61,621,335 $-42,480,446 $25,152,327 $-79,967,313
Cash Flow From Continuing Operating Activities $-61,621,335 $-42,480,446 $25,152,327 $-79,967,313
Operating Gains Losses $-274,308 $-402,708 $-1,265,320 $-3,157,465
Investing Activities
Capital Expenditure $-1,190,615 $-1,655,188 $-1,600,327 $-826,427
Investing Cash Flow $-1,190,615 $-4,754,289 $4,993,580 $-819,423
Cash Flow From Continuing Investing Activities $-1,190,615 $-4,754,289 $4,993,580 $-819,423
Net Other Investing Changes - $-3,099,101 $-2,744,251 -
Financing Activities
Issuance Of Capital Stock $0 $83,617,365 $0 $16,484,183
Financing Cash Flow $-2,143,107 $82,031,045 $-2,655,539 $-36,056,961
Cash Flow From Continuing Financing Activities $-2,143,107 $82,031,045 $-2,655,539 $-36,056,961
Net Common Stock Issuance $0 $83,617,365 $0 $16,484,183
Common Stock Issuance $0 $83,617,365 $0 $16,484,183
Other
Repayment Of Debt $-2,223,649 $-1,846,621 $-3,068,752 $-52,580,831
End Cash Position $107,870,895 $174,399,431 $138,817,549 $110,627,986
Beginning Cash Position $174,399,431 $138,817,549 $110,627,986 $218,891,083
Effect Of Exchange Rate Changes $-1,573,480 $785,573 $699,195 $8,580,600
Changes In Cash $-64,955,057 $34,796,310 $27,490,369 $-116,843,697
Proceeds From Stock Option Exercised $80,542 $260,301 $413,213 $39,687
Net Issuance Payments Of Debt $-2,223,649 $-1,846,621 $-3,068,752 $-52,580,831
Net Long Term Debt Issuance $-2,223,649 $-1,846,621 $-3,068,752 $-52,580,831
Long Term Debt Payments $-2,223,649 $-1,846,621 $-3,068,752 $-52,580,831
Net Investment Purchase And Sale $0 $0 $0 $0
Sale Of Investment $0 $19,843,585 $0 $0
Purchase Of Investment $0 $-19,843,585 $0 $0
Net Intangibles Purchase And Sale $0 $0 $9,268,121 $0
Sale Of Intangibles $0 $0 $9,268,121 $0
Net PPE Purchase And Sale $-1,190,615 $-1,655,188 $-1,530,291 $-819,423
Sale Of PPE $0 $0 $70,036 $7,004
Purchase Of PPE $-1,190,615 $-1,655,188 $-1,600,327 $-826,427
Taxes Refund Paid $-22,178 $229,952 $91,047 $-112,058
Interest Received Cfo $2,723,240 $3,794,794 $3,026,730 $123,731
Interest Paid Cfo $-604,646 $-898,798 $-920,976 $-4,386,600
Change In Working Capital $-20,330,336 $-15,482,665 $57,144,855 $-5,825,843
Change In Other Working Capital $-20,330,336 $-15,482,665 $57,144,855 $-5,825,843
Other Non Cash Items $-1,735,730 $-3,276,526 $-7,017,625 $1,930,664
Stock Based Compensation $4,685,421 $2,969,534 $3,625,540 $3,348,897
Deferred Tax $22,178 $-229,952 $-91,047 $112,058
Deferred Income Tax $22,178 $-229,952 $-91,047 $112,058
Depreciation Amortization Depletion $3,155,130 $3,222,832 $2,933,349 $2,942,687
Depreciation And Amortization $3,155,130 $3,222,832 $2,933,349 $2,942,687
Depreciation $3,155,130 $3,222,832 $2,933,349 $2,942,687
Gain Loss On Investment Securities $-274,308 $-402,708 $-1,112,408 $-3,166,803
Gain Loss On Sale Of Business $0 $0 $-152,912 $0
Net Income From Continuing Operations $-49,240,105 $-32,406,909 $-32,374,225 $-74,943,384
Earnings Losses From Equity Investments - $0 $0 $9,338
Issuance Of Debt - - $0 $0
Long Term Debt Issuance - - $0 $0
Fetched: 2026-08-25