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NCNA

NuCana plc

Price Chart
Latest Quote

$1.12

+0.08 (+7.69%)
Current Price
Previous Close $1.04
Open $1.05
Day High $1.13
Day Low $1.03
Volume 35,251
Fetched: 2026-10-27T18:56:17
Stock Information
Note: Financial values converted from GBP to USD
Shares Outstanding 4.16M
Total Debt $895K
Cash Equivalents $25.96M
Net Income $-12.93M
Sector Healthcare
Industry Biotechnology
Market Cap $4.66M
Exchange NCM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$-14.35M
Income$-12.93M
Book/sh$6.30
Cash/sh$4.69
Employees10
Financial Ratios
Quick Ratio4.56
Current Ratio4.73
Debt/Eq3.32
Returns & Margins
ROA-43.49%
ROE-70.26%
Ownership
Insider Ownership0.00%
Institutional Ownership2.60%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-0.12
P/B0.18
Analyst Data
Recommendationnone
Technical Indicators
SMA20$1.07
SMA50$1.27
SMA200$1.79
RSI47.49
ATR0.0594
Shares Float4.31M
Short Float2.40%
Short Ratio0.53
Volatility2.31
Rel Volume0.14
Performance History
Week+11.33%
Month-13.18%
Quarter-7.44%
6 Months-47.91%
YTD-69.23%
Year-73.71%
3 Years-99.96%
5 Years-99.99%
10 Years-100.00%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-10-27 $1.12 35,251
2026-10-26 $1.04 27,100
2026-10-23 $0.99 27,100
2026-10-22 $0.96 31,800
2026-10-21 $0.96 30,100
2026-10-20 $1.01 29,300
2026-10-19 $0.98 22,300
2026-10-16 $0.99 46,700
2026-10-15 $1.02 55,100
2026-10-14 $1.05 38,000
2026-10-13 $1.05 52,000
2026-10-12 $1.08 28,600
2026-10-09 $1.10 67,400
2026-10-08 $1.13 34,600
2026-10-07 $1.14 51,000
2026-10-06 $1.09 50,900
2026-10-05 $1.06 70,300
2026-10-02 $1.09 320,900
2026-10-01 $1.17 799,100
2026-09-30 $1.35 3,304,300
2026-09-29 $1.21 24,700
2026-09-28 $1.29 23,600
About NuCana plc

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer in the United States. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate concentrations of anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1b/2 modular clinical trial for patients with advanced solid tumors and lung cancer. It also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. It has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $0 $0 $0 $0
Operating Revenue $0 $0 $0 $0
Expenses
Total Expenses $27,570,007 $30,444,391 $41,190,249 $57,854,269
Other Income Expense $-13,331,745 $259,383 $-2,195,490 $6,080,938
Other Non Operating Income Expenses $2,449,579 - - -
Net Non Operating Interest Income Expense $510,825 $473,771 $997,830 $885,342
Operating Expense $27,570,007 $30,444,391 $41,190,249 $57,854,269
General And Administrative Expense $10,714,097 $6,601,027 $8,023,662 $9,648,775
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Net Interest Income $510,825 $473,771 $997,830 $885,342
Interest Income $510,825 $473,771 $997,830 $885,342
Normalized Income $-23,667,824 $-25,359,756 $-34,673,648 $-47,439,784
Net Income From Continuing And Discontinued Operation $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Total Operating Income As Reported $-26,613,202 $-30,185,009 $-43,385,739 $-51,773,331
Net Income Common Stockholders $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Net Income $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Net Income Including Noncontrolling Interests $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Net Income Continuous Operations $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Pretax Income $-40,390,927 $-29,711,238 $-42,387,909 $-50,887,989
Special Income Charges $1,112,964 $-43,672 $-665,661 $-386,427
Interest Income Non Operating $510,825 $473,771 $997,830 $885,342
Operating Income $-27,570,007 $-30,444,391 $-41,190,249 $-57,854,269
Per Share
Diluted EPS $0.00 $-1720.40 $-3506.96 $-4036.31
Basic EPS $0.00 $-1720.40 $-3506.96 $-4036.31
Other
Tax Effect Of Unusual Items $-603,931 $39,905 $-301,460 $1,017,153
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-11,426,076 $-30,012,969 $-38,233,815 $-62,966,492
Total Unusual Items $-15,781,324 $259,383 $-2,195,490 $6,080,938
Total Unusual Items Excluding Goodwill $-15,781,324 $259,383 $-2,195,490 $6,080,938
Reconciled Depreciation $362,607 $690,805 $760,944 $968,715
EBITDA (Bullshit earnings) $-27,207,400 $-29,753,586 $-40,429,305 $-56,885,554
EBIT $-27,570,007 $-30,444,391 $-41,190,249 $-57,854,269
Diluted Average Shares $5,507,875 $19,636 $13,915 $13,825
Basic Average Shares $5,507,875 $19,636 $13,915 $13,825
Diluted NI Availto Com Stockholders $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Tax Provision $-1,545,710 $-4,570,960 $-5,820,232 $-8,511,990
Other Special Charges $-1,112,964 - - -
Impairment Of Capital Assets $0 $43,672 $665,661 $386,427
Gain On Sale Of Security $-16,894,288 $303,054 $-1,529,829 $6,467,365
Research And Development $16,855,910 $23,843,364 $33,166,587 $48,205,495
Selling General And Administration $10,714,097 $6,601,027 $8,023,662 $9,648,775
Other Gand A $10,714,097 $6,601,027 $8,023,662 $9,648,775
Fetched: 2026-10-11
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $29,285,109 $4,969,298 $16,885,025 $47,823,037
Total Assets $39,481,764 $19,551,638 $36,804,563 $77,092,266
Total Non Current Assets $3,934,413 $3,320,364 $3,694,881 $4,412,154
Non Current Deferred Assets $154,836 $149,542 $189,244 $136,308
Non Current Deferred Taxes Assets $154,836 $149,542 $189,244 $136,308
Goodwill And Other Intangible Assets $2,908,793 $2,910,116 $2,816,156 $3,129,797
Other Intangible Assets $2,908,793 $2,910,116 $2,816,156 $3,129,797
Current Assets $35,547,350 $16,231,274 $33,109,682 $72,680,112
Prepaid Assets $987,243 $1,160,606 $2,605,738 $4,375,099
Receivables $2,466,783 $6,139,167 $7,708,697 $9,287,491
Other Receivables $54,259 $31,761 $51,612 $66,169
Taxes Receivable $2,412,524 $6,107,406 $7,657,085 $9,221,322
Cash Cash Equivalents And Short Term Investments $32,093,325 $8,931,502 $22,795,246 $55,465,565
Cash And Cash Equivalents $32,093,325 $8,931,502 $22,795,246 $55,465,565
Cash Financial $32,093,325 $8,931,502 $22,795,246 $55,465,565
Other Current Assets - - - $3,551,956
Other Non Current Assets - - - -
Debt
Total Debt $894,606 $251,442 $524,059 $845,641
Long Term Debt And Capital Lease Obligation $868,138 $154,836 $251,442 $524,059
Current Debt And Capital Lease Obligation $26,468 $96,607 $272,617 $321,582
Liabilities
Total Liabilities Net Minority Interest $7,287,862 $11,672,225 $17,103,383 $26,139,431
Total Non Current Liabilities Net Minority Interest $944,894 $203,801 $328,199 $584,935
Current Liabilities $6,342,968 $11,468,424 $16,775,184 $25,554,497
Payables And Accrued Expenses $6,316,500 $11,318,882 $16,502,567 $19,807,051
Payables $821,820 $3,757,080 $4,671,537 $6,570,589
Total Tax Payable $131,015 $177,333 $205,124 $214,388
Accounts Payable $690,805 $3,579,747 $4,466,413 $6,356,201
Equity
Common Stock Equity $32,193,902 $7,879,413 $19,701,180 $50,952,835
Total Equity Gross Minority Interest $32,193,902 $7,879,413 $19,701,180 $50,952,835
Stockholders Equity $32,193,902 $7,879,413 $19,701,180 $50,952,835
Gains Losses Not Affecting Retained Earnings $115,233,444 $103,780,901 $104,776,083 $100,407,601
Other Equity Adjustments $115,233,444 $103,780,901 $104,776,083 $100,407,601
Retained Earnings $-333,934,147 $-296,826,530 $-274,874,278 $-238,966,968
Other
Treasury Shares Number $661,691 $661,691 $661,691 $661,691
Ordinary Shares Number $27,539,377,055 $187,307,711 $69,292,699 $68,647,619
Share Issued $27,540,038,745 $187,969,401 $69,954,389 $69,309,310
Tangible Book Value $29,285,109 $4,969,298 $16,885,025 $47,823,037
Invested Capital $32,193,902 $7,879,413 $19,701,180 $50,952,835
Working Capital $29,204,383 $4,762,850 $16,334,498 $47,125,615
Capital Lease Obligations $894,606 $251,442 $524,059 $845,641
Total Capitalization $32,193,902 $7,879,413 $19,701,180 $50,952,835
Additional Paid In Capital $231,917,314 $193,406,913 $187,001,746 $186,739,717
Capital Stock $18,977,291 $7,518,130 $2,797,628 $2,772,484
Common Stock $18,977,291 $7,518,130 $2,797,628 $2,772,484
Long Term Capital Lease Obligation $868,138 $154,836 $251,442 $524,059
Long Term Provisions $76,756 $48,965 $76,756 $60,876
Current Capital Lease Obligation $26,468 $96,607 $272,617 $321,582
Current Accrued Expenses $5,494,680 $7,561,802 $11,831,031 $13,236,462
Net PPE $870,785 $260,706 $689,482 $1,146,048
Accumulated Depreciation $-1,341,909 $-1,237,362 $-2,345,032 $-1,893,759
Gross PPE $2,212,694 $1,498,068 $3,034,514 $3,039,807
Other Properties $1,447,779 $759,621 $1,770,684 $1,794,505
Machinery Furniture Equipment $764,915 $738,447 $1,263,829 $1,245,302
Current Provisions - $52,935 - $5,425,864
Fetched: 2026-10-11
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-10,137,102 $-25,688,158 $-35,621,460 $-31,332,380
Operating Activities
Operating Cash Flow $-9,881,690 $-25,300,408 $-34,988,883 $-30,646,869
Cash Flow From Continuing Operating Activities $-9,881,690 $-25,300,408 $-34,988,883 $-30,646,869
Operating Gains Losses $256,736 $-488,328 $1,556,297 $-6,635,435
Investing Activities
Capital Expenditure $-255,413 $-387,751 $-632,576 $-685,512
Investing Cash Flow $210,418 $104,547 $3,821,926 $158,806
Cash Flow From Continuing Investing Activities $210,418 $104,547 $3,821,926 $158,806
Net Other Investing Changes - - $3,435,498 -
Financing Activities
Issuance Of Capital Stock $26,712,456 $11,551,797 $329,522 $0
Financing Cash Flow $33,092,478 $10,830,554 $-70,139 $-213,064
Cash Flow From Continuing Financing Activities $33,092,478 $10,830,554 $-70,139 $-213,064
Net Other Financing Charges $-1,781,271 $-435,393 $-47,642 -
Net Common Stock Issuance $26,712,456 $11,551,797 $329,522 $0
Common Stock Issuance $26,712,456 $11,551,797 $329,522 $0
Other
Repayment Of Debt $-71,463 $-295,114 $-357,313 $-300,408
End Cash Position $32,093,325 $8,931,502 $22,795,246 $55,465,565
Beginning Cash Position $8,931,502 $22,795,246 $55,465,565 $79,752,263
Effect Of Exchange Rate Changes $-259,383 $501,562 $-1,433,222 $6,414,430
Changes In Cash $23,421,206 $-14,365,306 $-31,237,097 $-30,701,127
Proceeds From Stock Option Exercised $8,232,756 $9,264 $5,294 $87,343
Net Issuance Payments Of Debt $-71,463 $-295,114 $-357,313 $-300,408
Net Long Term Debt Issuance $-71,463 $-295,114 $-357,313 $-300,408
Long Term Debt Payments $-71,463 $-295,114 $-357,313 $-300,408
Interest Received Cfi $465,830 $492,298 $1,019,004 $844,317
Net Intangibles Purchase And Sale $-255,413 $-382,457 $-627,283 $-669,631
Purchase Of Intangibles $-255,413 $-382,457 $-627,283 $-669,631
Net PPE Purchase And Sale $0 $-5,294 $-5,294 $-15,881
Purchase Of PPE $0 $-5,294 $-5,294 $-15,881
Taxes Refund Paid $5,277,645 $5,313,377 $7,404,319 $9,554,814
Change In Working Capital $-4,859,457 $-2,888,942 $-1,695,252 $4,926,949
Change In Payables And Accrued Expense $-5,003,705 $-5,187,655 $-3,328,304 $4,520,671
Change In Payable $-5,003,705 $-5,187,655 $-3,328,304 $4,520,671
Change In Account Payable $-2,888,942 $-886,666 $-1,889,789 $3,935,737
Change In Tax Payable $-2,114,764 $-4,300,990 $-1,438,516 $584,935
Change In Income Tax Payable $-2,114,764 $-4,300,990 $-1,438,516 $584,935
Change In Prepaid Assets $144,249 $2,298,714 $1,633,053 $406,278
Other Non Cash Items $16,253,772 $-451,273 $-959,452 $-857,551
Stock Based Compensation $13,270,870 $2,178,286 $5,104,282 $6,471,336
Provisionand Write Offof Assets $-52,935 $13,234 $-5,437,775 $5,425,864
Asset Impairment Charge $0 $43,672 $665,661 $386,427
Deferred Tax $-1,545,710 $-4,570,960 $-5,820,232 $-8,511,990
Deferred Income Tax $-1,545,710 $-4,570,960 $-5,820,232 $-8,511,990
Depreciation Amortization Depletion $362,607 $690,805 $760,944 $968,715
Depreciation And Amortization $362,607 $690,805 $760,944 $968,715
Amortization Cash Flow $258,059 $244,826 $275,263 $968,715
Amortization Of Intangibles $258,059 $244,826 $275,263 $968,715
Depreciation $104,547 $445,980 $485,681 -
Net Foreign Currency Exchange Gain Loss $256,736 $-488,328 $1,556,297 $-6,635,435
Net Income From Continuing Operations $-38,845,217 $-25,140,278 $-36,567,678 $-42,375,999
Fetched: 2026-10-11