NCNA

NuCana plc

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$1.76

+0.29 (+19.73%)
Current Price
Previous Close $1.47
Open $1.45
Day High $1.90
Day Low $1.41
Volume 1,003,421
Fetched: 2026-08-30T22:07:37
Stock Information
Note: Financial values converted from GBP to USD
Shares Outstanding 4.16M
Total Debt $909K
Cash Equivalents $26.39M
Net Income $-13.14M
Sector Healthcare
Industry Biotechnology
Market Cap $7.33M
P/E Ratio 0.03
EPS (TTM) $67.98
Exchange NCM
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Recent Price History
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About NuCana plc

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer in the United States. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate concentrations of anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1b/2 modular clinical trial for patients with advanced solid tumors and lung cancer. It also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. It has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $0 $0 $0 $0
Operating Revenue $0 $0 $0 $0
Expenses
Total Expenses $28,191,943 $31,131,169 $42,119,436 $59,159,370
Other Income Expense $-13,632,488 $265,234 $-2,245,017 $6,218,114
Other Non Operating Income Expenses $2,504,838 - - -
Net Non Operating Interest Income Expense $522,349 $484,458 $1,020,339 $905,314
Operating Expense $28,191,943 $31,131,169 $42,119,436 $59,159,370
General And Administrative Expense $10,955,790 $6,749,936 $8,204,663 $9,866,436
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Net Interest Income $522,349 $484,458 $1,020,339 $905,314
Interest Income $522,349 $484,458 $1,020,339 $905,314
Normalized Income $-24,201,733 $-25,931,832 $-35,455,831 $-48,509,950
Net Income From Continuing And Discontinued Operation $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Total Operating Income As Reported $-27,213,554 $-30,865,935 $-44,364,453 $-52,941,256
Net Income Common Stockholders $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Net Income $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Net Income Including Noncontrolling Interests $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Net Income Continuous Operations $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Pretax Income $-41,302,082 $-30,381,477 $-43,344,114 $-52,035,942
Special Income Charges $1,138,071 $-44,657 $-680,677 $-395,145
Interest Income Non Operating $522,349 $484,458 $1,020,339 $905,314
Operating Income $-28,191,943 $-31,131,169 $-42,119,436 $-59,159,370
Per Share
Diluted EPS $0.00 $-1759.21 $-3586.07 $-4127.37
Basic EPS $0.00 $-1759.21 $-3586.07 $-4127.37
Other
Tax Effect Of Unusual Items $-617,555 $40,805 $-308,260 $1,040,099
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-11,683,830 $-30,690,014 $-39,096,309 $-64,386,917
Total Unusual Items $-16,137,326 $265,234 $-2,245,017 $6,218,114
Total Unusual Items Excluding Goodwill $-16,137,326 $265,234 $-2,245,017 $6,218,114
Reconciled Depreciation $370,786 $706,389 $778,110 $990,568
EBITDA (Bullshit earnings) $-27,821,156 $-30,424,780 $-41,341,326 $-58,168,802
EBIT $-28,191,943 $-31,131,169 $-42,119,436 $-59,159,370
Diluted Average Shares $5,632,124 $20,079 $14,229 $14,137
Basic Average Shares $5,632,124 $20,079 $14,229 $14,137
Diluted NI Availto Com Stockholders $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Tax Provision $-1,580,578 $-4,674,073 $-5,951,527 $-8,704,007
Other Special Charges $-1,138,071 - - -
Impairment Of Capital Assets $0 $44,657 $680,677 $395,145
Gain On Sale Of Security $-17,275,397 $309,891 $-1,564,340 $6,613,259
Research And Development $17,236,153 $24,381,233 $33,914,773 $49,292,934
Selling General And Administration $10,955,790 $6,749,936 $8,204,663 $9,866,436
Other Gand A $10,955,790 $6,749,936 $8,204,663 $9,866,436
Fetched: 2026-08-30
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $29,945,735 $5,081,397 $17,265,924 $48,901,850
Total Assets $40,372,410 $19,992,692 $37,634,816 $78,831,346
Total Non Current Assets $4,023,167 $3,395,266 $3,778,232 $4,511,685
Non Current Deferred Assets $158,328 $152,916 $193,513 $139,383
Non Current Deferred Taxes Assets $158,328 $152,916 $193,513 $139,383
Goodwill And Other Intangible Assets $2,974,410 $2,975,764 $2,879,684 $3,200,401
Other Intangible Assets $2,974,410 $2,975,764 $2,879,684 $3,200,401
Current Assets $36,349,243 $16,597,426 $33,856,584 $74,319,661
Prepaid Assets $1,009,513 $1,186,787 $2,664,520 $4,473,795
Receivables $2,522,430 $6,277,657 $7,882,593 $9,497,003
Other Receivables $55,483 $32,478 $52,776 $67,662
Taxes Receivable $2,466,947 $6,245,179 $7,829,817 $9,429,341
Cash Cash Equivalents And Short Term Investments $32,817,300 $9,132,982 $23,309,471 $56,716,781
Cash And Cash Equivalents $32,817,300 $9,132,982 $23,309,471 $56,716,781
Cash Financial $32,817,300 $9,132,982 $23,309,471 $56,716,781
Other Current Assets - - - $3,632,082
Other Non Current Assets - - - -
Debt
Total Debt $914,787 $257,115 $535,881 $864,717
Long Term Debt And Capital Lease Obligation $887,722 $158,328 $257,115 $535,881
Current Debt And Capital Lease Obligation $27,065 $98,786 $278,766 $328,836
Liabilities
Total Liabilities Net Minority Interest $7,452,265 $11,935,532 $17,489,208 $26,729,096
Total Non Current Liabilities Net Minority Interest $966,210 $208,398 $335,602 $598,130
Current Liabilities $6,486,055 $11,727,134 $17,153,606 $26,130,966
Payables And Accrued Expenses $6,458,990 $11,574,218 $16,874,839 $20,253,867
Payables $840,359 $3,841,834 $4,776,919 $6,718,811
Total Tax Payable $133,970 $181,333 $209,751 $219,224
Accounts Payable $706,389 $3,660,500 $4,567,168 $6,499,587
Equity
Common Stock Equity $32,920,145 $8,057,161 $20,145,608 $52,102,250
Total Equity Gross Minority Interest $32,920,145 $8,057,161 $20,145,608 $52,102,250
Stockholders Equity $32,920,145 $8,057,161 $20,145,608 $52,102,250
Gains Losses Not Affecting Retained Earnings $117,832,929 $106,122,034 $107,139,667 $102,672,638
Other Equity Adjustments $117,832,929 $106,122,034 $107,139,667 $102,672,638
Retained Earnings $-341,467,175 $-303,522,469 $-281,075,008 $-244,357,686
Other
Treasury Shares Number $676,617 $676,617 $676,617 $676,617
Ordinary Shares Number $28,160,621,978 $191,533,077 $70,855,833 $70,196,201
Share Issued $28,161,298,596 $192,209,695 $71,532,450 $70,872,819
Tangible Book Value $29,945,735 $5,081,397 $17,265,924 $48,901,850
Invested Capital $32,920,145 $8,057,161 $20,145,608 $52,102,250
Working Capital $29,863,188 $4,870,292 $16,702,978 $48,188,695
Capital Lease Obligations $914,787 $257,115 $535,881 $864,717
Total Capitalization $32,920,145 $8,057,161 $20,145,608 $52,102,250
Additional Paid In Capital $237,149,003 $197,769,868 $191,220,211 $190,952,270
Capital Stock $19,405,388 $7,687,727 $2,860,739 $2,835,027
Common Stock $19,405,388 $7,687,727 $2,860,739 $2,835,027
Long Term Capital Lease Obligation $887,722 $158,328 $257,115 $535,881
Long Term Provisions $78,488 $50,070 $78,488 $62,249
Current Capital Lease Obligation $27,065 $98,786 $278,766 $328,836
Current Accrued Expenses $5,618,631 $7,732,384 $12,097,920 $13,535,055
Net PPE $890,429 $266,587 $705,035 $1,171,901
Accumulated Depreciation $-1,372,180 $-1,265,275 $-2,397,932 $-1,936,479
Gross PPE $2,262,609 $1,531,862 $3,102,968 $3,108,381
Other Properties $1,480,439 $776,757 $1,810,628 $1,834,987
Machinery Furniture Equipment $782,170 $755,105 $1,292,339 $1,273,394
Current Provisions - $54,129 - $5,548,263
Fetched: 2026-08-30
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-10,365,779 $-26,267,643 $-36,425,024 $-32,039,189
Operating Activities
Operating Cash Flow $-10,104,605 $-25,871,145 $-35,778,178 $-31,338,214
Cash Flow From Continuing Operating Activities $-10,104,605 $-25,871,145 $-35,778,178 $-31,338,214
Operating Gains Losses $262,528 $-499,344 $1,591,404 $-6,785,120
Investing Activities
Capital Expenditure $-261,174 $-396,498 $-646,846 $-700,976
Investing Cash Flow $215,164 $106,906 $3,908,142 $162,388
Cash Flow From Continuing Investing Activities $215,164 $106,906 $3,908,142 $162,388
Net Other Investing Changes - - $3,512,998 -
Financing Activities
Issuance Of Capital Stock $27,315,046 $11,812,387 $336,955 $0
Financing Cash Flow $33,838,992 $11,074,874 $-71,721 $-217,871
Cash Flow From Continuing Financing Activities $33,838,992 $11,074,874 $-71,721 $-217,871
Net Other Financing Charges $-1,821,454 $-445,214 $-48,716 -
Net Common Stock Issuance $27,315,046 $11,812,387 $336,955 $0
Common Stock Issuance $27,315,046 $11,812,387 $336,955 $0
Other
Repayment Of Debt $-73,075 $-301,771 $-365,373 $-307,184
End Cash Position $32,817,300 $9,132,982 $23,309,471 $56,716,781
Beginning Cash Position $9,132,982 $23,309,471 $56,716,781 $81,551,348
Effect Of Exchange Rate Changes $-265,234 $512,876 $-1,465,553 $6,559,130
Changes In Cash $23,949,551 $-14,689,365 $-31,941,757 $-31,393,696
Proceeds From Stock Option Exercised $8,418,474 $9,473 $5,413 $89,314
Net Issuance Payments Of Debt $-73,075 $-301,771 $-365,373 $-307,184
Net Long Term Debt Issuance $-73,075 $-301,771 $-365,373 $-307,184
Long Term Debt Payments $-73,075 $-301,771 $-365,373 $-307,184
Interest Received Cfi $476,339 $503,403 $1,041,991 $863,364
Net Intangibles Purchase And Sale $-261,174 $-391,085 $-641,433 $-684,737
Purchase Of Intangibles $-261,174 $-391,085 $-641,433 $-684,737
Net PPE Purchase And Sale $0 $-5,413 $-5,413 $-16,239
Purchase Of PPE $0 $-5,413 $-5,413 $-16,239
Taxes Refund Paid $5,396,701 $5,433,238 $7,571,349 $9,770,356
Change In Working Capital $-4,969,079 $-2,954,112 $-1,733,494 $5,038,094
Change In Payables And Accrued Expense $-5,116,581 $-5,304,681 $-3,403,386 $4,622,650
Change In Payable $-5,116,581 $-5,304,681 $-3,403,386 $4,622,650
Change In Account Payable $-2,954,112 $-906,667 $-1,932,419 $4,024,521
Change In Tax Payable $-2,162,469 $-4,398,013 $-1,470,966 $598,130
Change In Income Tax Payable $-2,162,469 $-4,398,013 $-1,470,966 $598,130
Change In Prepaid Assets $147,503 $2,350,569 $1,669,892 $415,443
Other Non Cash Items $16,620,431 $-461,453 $-981,095 $-876,896
Stock Based Compensation $13,570,240 $2,227,425 $5,219,427 $6,617,319
Provisionand Write Offof Assets $-54,129 $13,532 $-5,560,442 $5,548,263
Asset Impairment Charge $0 $44,657 $680,677 $395,145
Deferred Tax $-1,580,578 $-4,674,073 $-5,951,527 $-8,704,007
Deferred Income Tax $-1,580,578 $-4,674,073 $-5,951,527 $-8,704,007
Depreciation Amortization Depletion $370,786 $706,389 $778,110 $990,568
Depreciation And Amortization $370,786 $706,389 $778,110 $990,568
Amortization Cash Flow $263,881 $250,348 $281,473 $990,568
Amortization Of Intangibles $263,881 $250,348 $281,473 $990,568
Depreciation $106,906 $456,040 $496,637 -
Net Foreign Currency Exchange Gain Loss $262,528 $-499,344 $1,591,404 $-6,785,120
Net Income From Continuing Operations $-39,721,504 $-25,707,403 $-37,392,587 $-43,331,935
Fetched: 2026-08-30