ANRO
Alto Neuroscience, Inc.
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Latest Quote
$35.13
| Previous Close | $36.30 |
| Open | $35.00 |
| Day High | $35.70 |
| Day Low | $34.73 |
| Volume | 246,713 |
Stock Information
| Shares Outstanding | 39.24M |
| Total Debt | $23.29M |
| Cash Equivalents | $243.73M |
| Net Income | $-84.24M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $1.38B |
| EPS (TTM) | $-2.32 |
| Exchange | NYQ |
Recent Price History
About Alto Neuroscience, Inc.
Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson's disease for patients with Parkinson's disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.
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Income Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Total Revenue | $0 | $0 | $0 | $0 |
| Operating Revenue | $0 | $0 | $0 | $0 |
| Expenses | ||||
| Interest Expense | $2,469,000 | $1,375,000 | $1,370,000 | $0 |
| Total Expenses | $66,364,000 | $68,610,000 | $37,809,000 | $27,455,000 |
| Other Income Expense | $-1,008,000 | $-297,000 | $525,000 | $-369,000 |
| Other Non Operating Income Expenses | $-327,000 | $-297,000 | $525,000 | - |
| Net Non Operating Interest Income Expense | $4,134,000 | $7,476,000 | $979,000 | $114,000 |
| Interest Expense Non Operating | $2,469,000 | $1,375,000 | $1,370,000 | $0 |
| Operating Expense | $66,364,000 | $68,610,000 | $37,809,000 | $27,455,000 |
| General And Administrative Expense | $20,745,000 | $21,614,000 | $7,518,000 | $5,504,000 |
| Other Operating Expenses | - | - | - | $-1,737,000 |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Net Interest Income | $4,134,000 | $7,476,000 | $979,000 | $114,000 |
| Interest Income | $6,603,000 | $8,851,000 | $2,349,000 | $114,000 |
| Normalized Income | $-62,557,000 | $-61,431,000 | $-36,305,000 | $-27,341,000 |
| Net Income From Continuing And Discontinued Operation | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Total Operating Income As Reported | $66,364,000 | $68,610,000 | $-37,809,000 | $-29,192,000 |
| Net Income Common Stockholders | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Net Income | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Net Income Including Noncontrolling Interests | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Net Income Continuous Operations | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Pretax Income | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Special Income Charges | $-681,000 | $0 | - | - |
| Interest Income Non Operating | $6,603,000 | $8,851,000 | $2,349,000 | $114,000 |
| Operating Income | $-66,364,000 | $-68,610,000 | $-37,809,000 | $-27,455,000 |
| Per Share | ||||
| Diluted EPS | $-2.19 | $-2.50 | $-1.42 | $-2.13 |
| Basic EPS | $-2.19 | $-2.50 | $-1.42 | $-2.13 |
| Other | ||||
| Tax Effect Of Unusual Items | $0 | $0 | $0 | $0 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-59,427,000 | $-59,554,000 | $-34,562,000 | $-26,999,000 |
| Total Unusual Items | $-681,000 | $0 | $525,000 | $-369,000 |
| Total Unusual Items Excluding Goodwill | $-681,000 | $0 | $525,000 | $-369,000 |
| Reconciled Depreciation | $661,000 | $502,000 | $373,000 | $342,000 |
| EBITDA (Bullshit earnings) | $-60,108,000 | $-59,554,000 | $-34,562,000 | $-27,368,000 |
| EBIT | $-60,769,000 | $-60,056,000 | $-34,935,000 | $-27,710,000 |
| Diluted Average Shares | $28,852,000 | $24,602,000 | $25,574,360 | $12,980,000 |
| Basic Average Shares | $28,852,000 | $24,602,000 | $25,574,360 | $12,980,000 |
| Diluted NI Availto Com Stockholders | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Other Special Charges | $681,000 | - | - | - |
| Research And Development | $45,619,000 | $46,996,000 | $30,291,000 | $23,688,000 |
| Selling General And Administration | $20,745,000 | $21,614,000 | $7,518,000 | $5,504,000 |
| Other Gand A | $20,745,000 | $21,614,000 | $7,518,000 | $5,504,000 |
| Gain On Sale Of Security | - | - | $525,000 | $-369,000 |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $151,142,000 | $151,460,000 | $-71,672,000 | $-38,406,000 |
| Total Assets | $184,689,000 | $177,542,000 | $86,628,000 | $50,854,000 |
| Total Non Current Assets | $6,971,000 | $8,205,000 | $1,237,000 | $1,634,000 |
| Other Non Current Assets | $838,000 | $504,000 | $131,000 | $461,000 |
| Current Assets | $177,718,000 | $169,337,000 | $85,391,000 | $49,220,000 |
| Prepaid Assets | $1,234,000 | $1,108,000 | $522,000 | $330,000 |
| Cash Cash Equivalents And Short Term Investments | $176,484,000 | $168,229,000 | $82,548,000 | $48,344,000 |
| Cash And Cash Equivalents | $176,484,000 | $168,229,000 | $82,548,000 | $48,344,000 |
| Other Current Assets | - | $30,000 | $112,000 | $213,000 |
| Current Deferred Assets | - | $0 | $2,209,000 | $0 |
| Receivables | - | - | $8,000 | $333,000 |
| Other Receivables | - | - | $8,000 | $333,000 |
| Accounts Receivable | - | - | - | $333,000 |
| Debt | ||||
| Total Debt | $23,958,000 | $16,944,000 | $9,986,000 | $9,748,000 |
| Long Term Debt And Capital Lease Obligation | $22,222,000 | $16,074,000 | $9,861,000 | $9,465,000 |
| Long Term Debt | $18,399,000 | $11,558,000 | $9,861,000 | $9,465,000 |
| Current Debt And Capital Lease Obligation | $1,736,000 | $870,000 | $125,000 | $283,000 |
| Current Debt | $585,000 | - | - | - |
| Other Current Borrowings | $585,000 | - | - | - |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $33,547,000 | $26,082,000 | $158,300,000 | $89,260,000 |
| Total Non Current Liabilities Net Minority Interest | $22,222,000 | $16,074,000 | $152,690,000 | $83,700,000 |
| Current Liabilities | $11,325,000 | $10,008,000 | $5,610,000 | $5,560,000 |
| Payables And Accrued Expenses | $9,589,000 | $9,138,000 | $5,485,000 | $5,277,000 |
| Interest Payable | $118,000 | $78,000 | $84,000 | $0 |
| Payables | $1,878,000 | $1,579,000 | $1,074,000 | $1,606,000 |
| Accounts Payable | $1,878,000 | $1,579,000 | $1,074,000 | $1,606,000 |
| Derivative Product Liabilities | - | $0 | $1,352,000 | $1,877,000 |
| Other Current Liabilities | - | - | $515,000 | - |
| Other Non Current Liabilities | - | - | - | $123,000 |
| Equity | ||||
| Common Stock Equity | $151,142,000 | $151,460,000 | $-71,672,000 | $-38,406,000 |
| Total Equity Gross Minority Interest | $151,142,000 | $151,460,000 | $-71,672,000 | $-38,406,000 |
| Stockholders Equity | $151,142,000 | $151,460,000 | $-71,672,000 | $-38,406,000 |
| Gains Losses Not Affecting Retained Earnings | $22,000 | $-101,000 | $-79,000 | $-46,000 |
| Other Equity Adjustments | $22,000 | $-101,000 | $-79,000 | $-46,000 |
| Retained Earnings | $-201,634,000 | $-138,396,000 | $-76,965,000 | $-40,660,000 |
| Preferred Securities Outside Stock Equity | - | $0 | $141,477,000 | $72,235,000 |
| Other | ||||
| Ordinary Shares Number | $31,923,521 | $26,986,560 | $25,574,360 | $25,574,360 |
| Share Issued | $31,923,521 | $26,986,560 | $25,574,360 | $25,574,360 |
| Tangible Book Value | $151,142,000 | $151,460,000 | $-71,672,000 | $-38,406,000 |
| Invested Capital | $170,126,000 | $163,018,000 | $-61,811,000 | $-28,941,000 |
| Working Capital | $166,393,000 | $159,329,000 | $79,781,000 | $43,660,000 |
| Capital Lease Obligations | $4,974,000 | $5,386,000 | $125,000 | $283,000 |
| Total Capitalization | $169,541,000 | $163,018,000 | $-61,811,000 | $-28,941,000 |
| Additional Paid In Capital | $352,751,000 | $289,954,000 | $5,372,000 | $2,300,000 |
| Capital Stock | $3,000 | $3,000 | $0 | $0 |
| Common Stock | $3,000 | $3,000 | $0 | $0 |
| Long Term Capital Lease Obligation | $3,823,000 | $4,516,000 | $0 | - |
| Current Capital Lease Obligation | $1,151,000 | $870,000 | $125,000 | $283,000 |
| Current Accrued Expenses | $7,711,000 | $7,559,000 | $4,411,000 | $3,671,000 |
| Net PPE | $6,133,000 | $7,701,000 | $1,106,000 | $1,173,000 |
| Accumulated Depreciation | $-1,526,000 | $-1,004,000 | $-684,000 | $-579,000 |
| Gross PPE | $7,659,000 | $8,705,000 | $1,790,000 | $1,752,000 |
| Leases | $246,000 | $246,000 | $0 | - |
| Other Properties | $6,386,000 | $7,341,000 | $1,201,000 | $1,132,000 |
| Machinery Furniture Equipment | $1,027,000 | $1,118,000 | $589,000 | $620,000 |
| Properties | $0 | $0 | $0 | - |
| Buildings And Improvements | - | $5,035,000 | $0 | - |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-51,793,000 | $-49,499,000 | $-33,918,000 | $-21,126,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-51,769,000 | $-47,424,000 | $-33,448,000 | $-20,394,000 |
| Cash Flow From Continuing Operating Activities | $-51,769,000 | $-47,424,000 | $-33,448,000 | $-20,394,000 |
| Operating Gains Losses | $837,000 | $52,000 | $140,000 | $369,000 |
| Investing Activities | ||||
| Capital Expenditure | $-24,000 | $-2,075,000 | $-470,000 | $-732,000 |
| Investing Cash Flow | $-24,000 | $-2,075,000 | $-470,000 | $-732,000 |
| Cash Flow From Continuing Investing Activities | $-24,000 | $-2,075,000 | $-470,000 | $-732,000 |
| Capital Expenditure Reported | $-24,000 | $-2,075,000 | $-470,000 | $-732,000 |
| Financing Activities | ||||
| Repurchase Of Capital Stock | $-167,000 | $0 | - | - |
| Issuance Of Capital Stock | $50,000,000 | $137,579,000 | $70,000,000 | $34,305,000 |
| Financing Cash Flow | $60,078,000 | $135,691,000 | $68,130,000 | $43,789,000 |
| Cash Flow From Continuing Financing Activities | $60,078,000 | $135,691,000 | $68,130,000 | $43,789,000 |
| Net Other Financing Charges | $67,000 | $-2,075,000 | $-2,051,000 | $-341,000 |
| Net Common Stock Issuance | $49,833,000 | $137,579,000 | $0 | $43,000 |
| Common Stock Issuance | $50,000,000 | $137,579,000 | $0 | $43,000 |
| Net Preferred Stock Issuance | - | $0 | $70,000,000 | $34,262,000 |
| Preferred Stock Issuance | - | $0 | $70,000,000 | $34,262,000 |
| Other | ||||
| Repayment Of Debt | $-10,213,000 | $0 | - | - |
| Issuance Of Debt | $19,688,000 | $0 | $0 | $9,825,000 |
| Interest Paid Supplemental Data | $1,660,000 | $999,000 | $912,000 | $0 |
| End Cash Position | $176,984,000 | $168,729,000 | $82,548,000 | $48,344,000 |
| Beginning Cash Position | $168,729,000 | $82,548,000 | $48,344,000 | $25,705,000 |
| Effect Of Exchange Rate Changes | $-30,000 | $-11,000 | $-8,000 | $-24,000 |
| Changes In Cash | $8,285,000 | $86,192,000 | $34,212,000 | $22,663,000 |
| Proceeds From Stock Option Exercised | $703,000 | $187,000 | $181,000 | - |
| Common Stock Payments | $-167,000 | $0 | - | - |
| Net Issuance Payments Of Debt | $9,475,000 | $0 | $0 | $9,825,000 |
| Net Long Term Debt Issuance | $9,475,000 | $0 | $0 | $9,825,000 |
| Long Term Debt Payments | $-10,213,000 | $0 | - | - |
| Long Term Debt Issuance | $19,688,000 | $0 | $0 | $9,825,000 |
| Change In Working Capital | $33,000 | $4,060,000 | $-698,000 | $4,579,000 |
| Change In Payables And Accrued Expense | $-68,000 | $4,523,000 | $-989,000 | $3,480,000 |
| Change In Accrued Expense | $-289,000 | $4,007,000 | $-357,000 | $2,474,000 |
| Change In Payable | $221,000 | $516,000 | $-632,000 | $1,006,000 |
| Change In Account Payable | $221,000 | $516,000 | $-632,000 | $1,006,000 |
| Change In Prepaid Assets | $101,000 | $-463,000 | $291,000 | $-59,000 |
| Other Non Cash Items | $1,830,000 | $1,762,000 | $151,000 | $263,000 |
| Stock Based Compensation | $8,108,000 | $7,631,000 | $2,891,000 | $1,763,000 |
| Depreciation Amortization Depletion | $661,000 | $502,000 | $373,000 | $342,000 |
| Depreciation And Amortization | $661,000 | $502,000 | $373,000 | $342,000 |
| Depreciation | $661,000 | $502,000 | - | - |
| Net Income From Continuing Operations | $-63,238,000 | $-61,431,000 | $-36,305,000 | $-27,710,000 |
| Change In Receivables | - | - | $325,000 | $1,158,000 |
| Changes In Account Receivables | - | - | $325,000 | $1,158,000 |
| Gain Loss On Investment Securities | - | - | $-525,000 | $369,000 |