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ACIU

AC Immune SA

Price Chart
Latest Quote

$2.66

+0.02 (+0.76%)
Current Price
Previous Close $2.64
Open $2.62
Day High $2.68
Day Low $2.58
Volume 31,232
Fetched: 2026-09-01T16:22:40
Stock Information
Note: Financial values converted from CHF to USD
Shares Outstanding 99.43M
Total Debt $5.05M
Cash Equivalents $92.79M
Revenue $21.56M
Net Income $-53.14M
Sector Healthcare
Industry Biotechnology
Market Cap $264.48M
EPS (TTM) $-0.53
Exchange NGM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$192.23M
Sales$21.56M
Income$-53.14M
Book/sh$0.44
Cash/sh$0.76
Employees90
Financial Ratios
Quick Ratio0.89
Current Ratio0.93
Debt/Eq11.66
Returns & Margins
ROA-16.04%
ROE-78.53%
Gross Margin-162.23%
Operating Margin7.89%
Profit Margin-246.48%
Ownership
Insider Ownership37.90%
Institutional Ownership24.35%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E4.34
P/S15.11
P/B6.08
Analyst Data
Recommendationstrong_buy
Target Price$8.49
Technical Indicators
SMA20$2.58
SMA50$2.46
SMA200$2.84
RSI55.88
ATR0.1542
Shares Float39.19M
Short Float7.33%
Short Ratio16.29
Volatility1.57
Rel Volume0.13
Performance History
Week-6.99%
Month+21.46%
Quarter+8.13%
6 Months-7.64%
YTD-20.83%
Year+29.76%
3 Years-14.19%
5 Years-60.42%
10 Years-83.01%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-09-01 $2.66 31,232
2026-08-31 $2.64 133,000
2026-08-27 $2.71 169,400
2026-08-26 $2.85 269,100
2026-08-25 $2.92 241,300
2026-08-24 $2.86 370,600
2026-08-21 $2.90 442,000
2026-08-20 $2.64 237,100
2026-08-19 $2.58 280,700
2026-08-18 $2.57 90,200
2026-08-17 $2.53 104,600
2026-08-14 $2.49 133,200
2026-08-13 $2.57 217,300
2026-08-12 $2.62 380,500
2026-08-11 $2.54 1,057,100
2026-08-10 $2.28 105,400
2026-08-07 $2.36 76,900
2026-08-06 $2.32 70,300
2026-08-05 $2.29 145,000
2026-08-04 $2.27 106,000
2026-08-03 $2.22 118,300
About AC Immune SA

AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $4,414,927 $33,743,978 $18,288,645 $4,862,227
Operating Revenue $4,414,927 $33,743,978 $18,288,645 $4,862,227
Expenses
Interest Expense $236,006 $164,340 $217,472 $438,651
Total Expenses $89,504,515 $98,464,110 $84,548,380 $92,403,316
Other Income Expense $-4,025,701 $-1,974,546 $-1,812,678 $485,605
Net Non Operating Interest Income Expense $2,068,454 $3,784,752 $1,072,532 $-353,392
Interest Expense Non Operating $236,006 $164,340 $217,472 $438,651
Operating Expense $89,504,515 $98,464,110 $84,548,380 $92,403,316
Other Operating Expenses $3,374,521 $5,597,430 $2,683,801 $6,010,133
General And Administrative Expense $14,397,628 $14,128,260 $13,068,084 $11,839,862
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Net Interest Income $2,068,454 $3,784,752 $1,072,532 $-353,392
Interest Income $2,304,461 $3,949,092 $1,290,004 $85,259
Normalized Income $-83,021,134 $-61,106,923 $-65,353,636 $-87,847,416
Net Income From Continuing And Discontinued Operation $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Total Operating Income As Reported $-85,651,802 $-64,720,132 $-66,259,734 $-87,541,090
Net Income Common Stockholders $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Net Income $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Net Income Including Noncontrolling Interests $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Net Income Continuous Operations $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Pretax Income $-87,046,835 $-62,909,925 $-66,999,880 $-87,408,876
Special Income Charges $-562,214 $0 $0 -
Interest Income Non Operating $2,304,461 $3,949,092 $1,290,004 $85,259
Operating Income $-85,089,588 $-64,720,132 $-66,259,734 $-87,541,090
Depreciation Amortization Depletion Income Statement $1,998,023 $1,424,688 $1,323,366 -
Depreciation And Amortization In Income Statement $1,998,023 $1,424,688 $1,323,366 -
Depreciation Income Statement $1,998,023 $1,424,688 $1,323,366 -
Per Share
Diluted EPS $-0.86 $-0.63 $-0.79 $-1.05
Basic EPS $-0.86 $-0.63 $-0.79 $-1.05
Other
Tax Effect Of Unusual Items $0 $-167,836 $-154,078 $63,129
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-79,692,331 $-58,099,595 $-62,232,797 $-84,540,966
Total Unusual Items $-4,025,701 $-1,974,546 $-1,812,678 $485,605
Total Unusual Items Excluding Goodwill $-4,025,701 $-1,974,546 $-1,812,678 $485,605
Reconciled Depreciation $3,092,796 $2,671,445 $2,736,933 $2,914,865
EBITDA (Bullshit earnings) $-83,718,032 $-60,074,141 $-64,045,475 $-84,055,361
EBIT $-86,810,829 $-62,745,586 $-66,782,408 $-86,970,226
Diluted Average Shares $124,492,414 $123,360,063 $104,651,700 $103,242,823
Basic Average Shares $124,492,414 $123,360,063 $104,651,700 $103,242,823
Diluted NI Availto Com Stockholders $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Tax Provision $0 $3,707 $12,356 $16,063
Restructuring And Mergern Acquisition $562,214 $0 $0 -
Gain On Sale Of Security $-3,463,487 $-1,974,546 $-1,812,678 $485,605
Research And Development $69,734,342 $77,313,732 $67,473,128 $74,553,322
Selling General And Administration $14,397,628 $14,128,260 $13,068,084 $11,839,862
Salaries And Wages $14,397,628 $14,128,260 $13,068,084 $11,839,862
Fetched: 2026-08-30
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $-6,835,537 $76,429,017 $136,200,427 $146,515,515
Total Assets $190,598,058 $285,324,369 $225,891,523 $229,751,649
Total Non Current Assets $71,084,892 $72,802,426 $71,247,996 $71,474,117
Other Non Current Assets $1,236 - - -
Investmentin Financial Assets $721,611 $512,789 $446,065 $446,065
Goodwill And Other Intangible Assets $62,295,814 $62,295,814 $62,295,814 $62,295,814
Other Intangible Assets $62,295,814 $62,295,814 $62,295,814 $62,295,814
Current Assets $119,513,166 $212,521,944 $154,643,527 $158,277,532
Prepaid Assets $4,907,945 $5,315,705 $7,953,788 $5,817,373
Receivables $1,653,281 $2,722,106 $19,359,942 $988,509
Other Receivables $543,680 $1,535,895 $359,570 $657,358
Taxes Receivable $1,109,601 $1,186,210 $712,962 $331,150
Cash Cash Equivalents And Short Term Investments $112,951,940 $204,484,133 $127,329,798 $151,471,650
Cash And Cash Equivalents $33,108,861 $44,822,689 $96,989,996 $39,028,792
Accounts Receivable - $0 $18,287,410 $0
Debt
Total Debt $5,611,022 $6,705,795 $4,321,018 $3,461,016
Long Term Debt And Capital Lease Obligation $4,558,260 $5,438,033 $3,490,671 $2,783,887
Current Debt And Capital Lease Obligation $1,052,762 $1,267,762 $830,347 $677,128
Liabilities
Total Liabilities Net Minority Interest $135,137,781 $146,599,538 $27,395,281 $20,940,320
Total Non Current Liabilities Net Minority Interest $18,131,720 $22,000,495 $10,620,290 $6,753,985
Non Current Deferred Liabilities $2,890,152 $5,634,499 $0 -
Current Liabilities $117,006,061 $124,599,043 $16,774,992 $14,186,335
Current Deferred Liabilities $103,430,130 $105,098,239 $170,518 $725,318
Payables And Accrued Expenses $12,523,169 $18,233,042 $15,774,127 $12,783,888
Payables $2,555,295 $3,284,320 $2,074,633 $1,147,906
Accounts Payable $2,555,295 $3,284,320 $2,074,633 $1,147,906
Equity
Common Stock Equity $55,460,277 $138,724,831 $198,496,242 $208,811,329
Total Equity Gross Minority Interest $55,460,277 $138,724,831 $198,496,242 $208,811,329
Stockholders Equity $55,460,277 $138,724,831 $198,496,242 $208,811,329
Gains Losses Not Affecting Retained Earnings $8,649 $-6,178 $-63,017 $12,356
Retained Earnings $-542,470,065 $-455,009,291 $-390,704,333 $-326,226,386
Other
Treasury Shares Number $13,468,150 $13,468,150 $6,479,622 $7,678,267
Ordinary Shares Number $125,716,343 $124,070,657 $122,572,389 $103,324,315
Share Issued $139,184,493 $137,538,806 $129,052,011 $111,002,582
Tangible Book Value $-6,835,537 $76,429,017 $136,200,427 $146,515,515
Invested Capital $55,460,277 $138,724,831 $198,496,242 $208,811,329
Working Capital $2,507,105 $87,922,901 $137,868,536 $144,091,198
Capital Lease Obligations $5,611,022 $6,705,795 $4,321,018 $3,461,016
Total Capitalization $55,460,277 $138,724,831 $198,496,242 $208,811,329
Foreign Currency Translation Adjustments $8,649 $-6,178 $-63,017 $12,356
Treasury Stock $269,369 $269,369 $129,742 $153,219
Additional Paid In Capital $595,407,173 $591,259,144 $586,812,091 $532,958,140
Capital Stock $2,783,887 $2,750,525 $2,581,243 $2,220,438
Common Stock $2,783,887 $2,750,525 $2,581,243 $2,220,438
Employee Benefits $10,683,307 $10,927,963 $7,129,619 $3,970,098
Non Current Deferred Revenue $2,890,152 $5,634,499 $0 -
Long Term Capital Lease Obligation $4,558,260 $5,438,033 $3,490,671 $2,783,887
Current Deferred Revenue $103,430,130 $105,098,239 $170,518 $725,318
Current Capital Lease Obligation $1,052,762 $1,267,762 $830,347 $677,128
Current Accrued Expenses $9,967,874 $14,948,722 $13,699,494 $11,635,982
Investments And Advances $721,611 $512,789 $446,065 $446,065
Net PPE $8,066,231 $9,993,822 $8,506,117 $8,732,238
Accumulated Depreciation $-16,947,981 $-15,405,907 $-13,587,051 $-11,544,545
Gross PPE $25,014,211 $25,399,730 $22,093,168 $20,276,783
Leases $2,335,352 $2,301,989 $2,053,627 $2,026,443
Other Properties $13,511,677 $13,018,659 $12,644,261 $12,065,984
Machinery Furniture Equipment $3,645,126 $3,505,499 $3,137,279 $2,834,549
Buildings And Improvements $5,522,056 $6,573,582 $4,258,001 $3,346,102
Properties $0 $0 $0 $0
Other Short Term Investments $79,843,078 $159,661,444 $30,339,801 $112,442,858
Construction In Progress - $0 $0 $3,707
Fetched: 2026-08-30
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-86,694,679 $80,645,006 $-75,632,032 $-92,434,207
Operating Activities
Operating Cash Flow $-85,582,607 $81,356,732 $-74,642,287 $-90,903,255
Cash Flow From Continuing Operating Activities $-85,582,607 $81,356,732 $-74,642,287 $-90,903,255
Operating Gains Losses $-1,935,006 $-12,356 $1,097,245 $668,479
Investing Activities
Capital Expenditure $-1,112,072 $-711,726 $-989,744 $-1,530,953
Investing Cash Flow $78,514,770 $-130,100,093 $81,113,312 $29,362,414
Cash Flow From Continuing Investing Activities $78,514,770 $-130,100,093 $81,113,312 $29,362,414
Net Other Investing Changes $-210,058 $-66,724 - $2,471
Financing Activities
Issuance Of Capital Stock $7,414 $137,156 $54,118,377 $8,649
Financing Cash Flow $-1,260,349 $-1,383,912 $53,441,248 $-1,663,166
Cash Flow From Continuing Financing Activities $-1,260,349 $-1,383,912 $53,441,248 $-1,663,166
Net Common Stock Issuance $7,414 $137,156 $54,118,377 $-1,236
Common Stock Issuance $7,414 $137,156 $54,118,377 $8,649
Net Other Financing Charges - $-677,128 - $-958,853
Repurchase Of Capital Stock - - - $-9,885
Other
Repayment Of Debt $-1,267,762 $-843,939 $-677,128 $-703,077
End Cash Position $33,108,861 $44,822,689 $96,989,996 $39,028,792
Beginning Cash Position $44,822,689 $96,989,996 $39,028,792 $101,589,033
Effect Of Exchange Rate Changes $-3,385,642 $-2,040,035 $-1,951,069 $643,766
Changes In Cash $-8,328,185 $-50,127,273 $59,912,273 $-63,204,007
Net Issuance Payments Of Debt $-1,267,762 $-843,939 $-677,128 $-703,077
Net Long Term Debt Issuance $-1,267,762 $-843,939 $-677,128 $-703,077
Long Term Debt Payments $-1,267,762 $-843,939 $-677,128 $-703,077
Net Investment Purchase And Sale $79,818,366 $-129,321,643 $82,103,056 $30,890,895
Net PPE Purchase And Sale $-1,093,538 $-711,726 $-989,744 $-1,530,953
Sale Of PPE $18,535 $0 $0 $0
Purchase Of PPE $-1,112,072 $-711,726 $-989,744 $-1,530,953
Interest Received Cfo $2,344,001 $1,931,299 $735,203 $85,259
Interest Paid Cfo $-233,535 $-159,397 $-217,472 $-590,634
Change In Working Capital $-8,371,433 $132,848,147 $-18,732,239 $-10,418,881
Change In Other Working Capital $-4,412,455 $110,562,220 $-554,800 $-160,633
Change In Payables And Accrued Expense $-5,502,286 $2,903,744 $2,356,357 $-8,880,514
Change In Accrued Expense $-4,770,790 $1,696,528 $1,404,918 $-7,554,677
Change In Payable $-731,496 $1,207,216 $951,440 $-1,325,837
Change In Prepaid Assets $407,760 $2,638,082 $-2,159,891 $-2,122,822
Change In Receivables $1,135,549 $16,744,101 $-18,373,904 $745,088
Changes In Account Receivables $0 $18,287,410 $-18,287,410 $0
Other Non Cash Items $1,135,549 $232,300 $1,356,728 $-252,070
Stock Based Compensation $5,431,855 $6,758,928 $5,393,550 $4,114,667
Depreciation Amortization Depletion $3,092,796 $2,671,445 $2,736,933 $2,914,865
Depreciation And Amortization $3,092,796 $2,671,445 $2,736,933 $2,914,865
Depreciation $3,092,796 $2,671,445 $2,736,933 $2,914,865
Pension And Employee Benefit Expense $-1,916,471 $-12,356 $1,097,245 $668,479
Gain Loss On Sale Of PPE $-18,535 $0 $0 $0
Net Income From Continuing Operations $-87,046,835 $-62,913,632 $-67,012,236 $-87,424,940
Issuance Of Debt - - $0 $0
Long Term Debt Issuance - - $0 $0
Proceeds From Stock Option Exercised - - - $8,649
Common Stock Payments - - - $-9,885
Net Short Term Debt Issuance - - - $0
Short Term Debt Payments - - - $0
Fetched: 2026-08-30