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ACIU

AC Immune SA

Price Chart
Latest Quote

$2.18

-0.18 (-7.63%)
Current Price
Previous Close $2.36
Open $2.35
Day High $2.35
Day Low $2.15
Volume 238,878
Fetched: 2026-07-17T03:47:10
Stock Information
Note: Financial values converted from CHF to USD
Shares Outstanding 101.77M
Total Debt $5.33M
Cash Equivalents $92.69M
Revenue $4.59M
Net Income $-82.06M
Sector Healthcare
Industry Biotechnology
Market Cap $223.90M
EPS (TTM) $-0.82
Exchange NGM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$146.59M
Sales$4.59M
Income$-82.06M
Book/sh$0.40
Cash/sh$0.73
Employees90
Financial Ratios
Quick Ratio0.83
Current Ratio0.87
Debt/Eq13.65
Returns & Margins
ROA-23.06%
ROE-104.83%
Operating Margin-1321.54%
Ownership
Insider Ownership37.90%
Institutional Ownership24.83%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E6.82
P/S60.48
P/B5.56
Analyst Data
Recommendationstrong_buy
Target Price$8.53
Technical Indicators
SMA20$2.45
SMA50$2.55
SMA200$2.97
RSI35.00
ATR0.1592
Shares Float38.75M
Short Float6.92%
Short Ratio10.54
Volatility1.57
Rel Volume1.28
Performance History
Week-7.95%
Month-7.17%
Quarter-28.34%
6 Months-40.05%
YTD-34.52%
Year+6.80%
3 Years-29.49%
5 Years-72.77%
10 Years-85.95%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-07-17 $2.20 353,400
2026-07-16 $2.18 238,900
2026-07-15 $2.36 64,000
2026-07-14 $2.41 165,000
2026-07-13 $2.45 250,000
2026-07-10 $2.39 199,700
2026-07-09 $2.60 289,900
2026-07-08 $2.52 164,100
2026-07-07 $2.54 141,500
2026-07-06 $2.51 269,200
2026-07-02 $2.51 364,500
2026-07-01 $2.38 687,300
2026-06-30 $2.38 585,800
2026-06-29 $2.66 142,400
2026-06-26 $2.56 259,200
2026-06-25 $2.45 173,500
2026-06-24 $2.54 463,300
2026-06-23 $2.45 149,400
2026-06-22 $2.50 350,300
2026-06-18 $2.40 213,300
About AC Immune SA

AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $4,403,555 $33,657,059 $18,241,537 $4,849,703
Operating Revenue $4,403,555 $33,657,059 $18,241,537 $4,849,703
Expenses
Interest Expense $235,399 $163,916 $216,912 $437,521
Total Expenses $89,273,966 $98,210,482 $84,330,597 $92,165,300
Other Income Expense $-4,015,332 $-1,969,460 $-1,808,009 $484,354
Net Non Operating Interest Income Expense $2,063,126 $3,775,004 $1,069,769 $-352,482
Interest Expense Non Operating $235,399 $163,916 $216,912 $437,521
Operating Expense $89,273,966 $98,210,482 $84,330,597 $92,165,300
Other Operating Expenses $3,365,829 $5,583,012 $2,676,888 $5,994,651
General And Administrative Expense $14,360,542 $14,091,868 $13,034,423 $11,809,365
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Net Interest Income $2,063,126 $3,775,004 $1,069,769 $-352,482
Interest Income $2,298,525 $3,938,920 $1,286,681 $85,039
Normalized Income $-82,807,285 $-60,949,521 $-65,185,296 $-87,621,135
Net Income From Continuing And Discontinued Operation $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Total Operating Income As Reported $-85,431,177 $-64,553,423 $-66,089,060 $-87,315,598
Net Income Common Stockholders $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Net Income $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Net Income Including Noncontrolling Interests $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Net Income Continuous Operations $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Pretax Income $-86,822,616 $-62,747,880 $-66,827,299 $-87,183,725
Special Income Charges $-560,766 $0 $0 -
Interest Income Non Operating $2,298,525 $3,938,920 $1,286,681 $85,039
Operating Income $-84,870,411 $-64,553,423 $-66,089,060 $-87,315,598
Depreciation Amortization Depletion Income Statement $1,992,877 $1,421,018 $1,319,957 -
Depreciation And Amortization In Income Statement $1,992,877 $1,421,018 $1,319,957 -
Depreciation Income Statement $1,992,877 $1,421,018 $1,319,957 -
Per Share
Diluted EPS $-0.86 $-0.63 $-0.79 $-1.05
Basic EPS $-0.86 $-0.63 $-0.79 $-1.05
Other
Tax Effect Of Unusual Items $0 $-167,404 $-153,681 $62,966
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-79,487,056 $-57,949,940 $-62,072,495 $-84,323,202
Total Unusual Items $-4,015,332 $-1,969,460 $-1,808,009 $484,354
Total Unusual Items Excluding Goodwill $-4,015,332 $-1,969,460 $-1,808,009 $484,354
Reconciled Depreciation $3,084,830 $2,664,563 $2,729,883 $2,907,357
EBITDA (Bullshit earnings) $-83,502,388 $-59,919,400 $-63,880,504 $-83,838,848
EBIT $-86,587,218 $-62,583,963 $-66,610,387 $-86,746,204
Diluted Average Shares $124,171,741 $123,042,308 $104,382,134 $102,976,886
Basic Average Shares $124,171,741 $123,042,308 $104,382,134 $102,976,886
Diluted NI Availto Com Stockholders $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Tax Provision $0 $3,697 $12,325 $16,022
Restructuring And Mergern Acquisition $560,766 $0 $0 -
Gain On Sale Of Security $-3,454,566 $-1,969,460 $-1,808,009 $484,354
Research And Development $69,554,718 $77,114,584 $67,299,329 $74,361,284
Selling General And Administration $14,360,542 $14,091,868 $13,034,423 $11,809,365
Salaries And Wages $14,360,542 $14,091,868 $13,034,423 $11,809,365
Fetched: 2026-06-24
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $-6,817,930 $76,232,148 $135,849,597 $146,138,114
Total Assets $190,107,108 $284,589,420 $225,309,663 $229,159,846
Total Non Current Assets $70,901,789 $72,614,898 $71,064,472 $71,290,011
Other Non Current Assets $1,232 - - -
Investmentin Financial Assets $719,753 $511,468 $444,916 $444,916
Goodwill And Other Intangible Assets $62,135,350 $62,135,350 $62,135,350 $62,135,350
Other Intangible Assets $62,135,350 $62,135,350 $62,135,350 $62,135,350
Current Assets $119,205,319 $211,974,521 $154,245,190 $157,869,835
Prepaid Assets $4,895,303 $5,302,013 $7,933,300 $5,802,389
Receivables $1,649,022 $2,715,094 $19,310,074 $985,962
Other Receivables $542,279 $1,531,939 $358,644 $655,665
Taxes Receivable $1,106,743 $1,183,155 $711,125 $330,297
Cash Cash Equivalents And Short Term Investments $112,660,994 $203,957,415 $127,001,817 $151,081,483
Cash And Cash Equivalents $33,023,578 $44,707,233 $96,740,166 $38,928,260
Accounts Receivable - $0 $18,240,304 $0
Debt
Total Debt $5,596,569 $6,688,522 $4,309,888 $3,452,101
Long Term Debt And Capital Lease Obligation $4,546,519 $5,424,026 $3,481,680 $2,776,717
Current Debt And Capital Lease Obligation $1,050,050 $1,264,497 $828,208 $675,384
Liabilities
Total Liabilities Net Minority Interest $134,789,687 $146,221,921 $27,324,715 $20,886,381
Total Non Current Liabilities Net Minority Interest $18,085,015 $21,943,826 $10,592,934 $6,736,588
Non Current Deferred Liabilities $2,882,708 $5,619,986 $0 -
Current Liabilities $116,704,672 $124,278,096 $16,731,782 $14,149,793
Current Deferred Liabilities $103,163,711 $104,827,522 $170,079 $723,450
Payables And Accrued Expenses $12,490,911 $18,186,076 $15,733,495 $12,750,959
Payables $2,548,713 $3,275,860 $2,069,289 $1,144,949
Accounts Payable $2,548,713 $3,275,860 $2,069,289 $1,144,949
Equity
Common Stock Equity $55,317,420 $138,367,498 $197,984,947 $208,273,465
Total Equity Gross Minority Interest $55,317,420 $138,367,498 $197,984,947 $208,273,465
Stockholders Equity $55,317,420 $138,367,498 $197,984,947 $208,273,465
Gains Losses Not Affecting Retained Earnings $8,627 $-6,162 $-62,855 $12,325
Retained Earnings $-541,072,749 $-453,837,260 $-389,697,941 $-325,386,079
Other
Treasury Shares Number $13,433,458 $13,433,458 $6,462,932 $7,658,489
Ordinary Shares Number $125,392,518 $123,751,070 $122,256,662 $103,058,168
Share Issued $138,825,976 $137,184,528 $128,719,594 $110,716,657
Tangible Book Value $-6,817,930 $76,232,148 $135,849,597 $146,138,114
Invested Capital $55,317,420 $138,367,498 $197,984,947 $208,273,465
Working Capital $2,500,647 $87,696,426 $137,513,408 $143,720,042
Capital Lease Obligations $5,596,569 $6,688,522 $4,309,888 $3,452,101
Total Capitalization $55,317,420 $138,367,498 $197,984,947 $208,273,465
Foreign Currency Translation Adjustments $8,627 $-6,162 $-62,855 $12,325
Treasury Stock $268,675 $268,675 $129,408 $152,824
Additional Paid In Capital $593,873,500 $589,736,155 $585,300,557 $531,585,325
Capital Stock $2,776,717 $2,743,440 $2,574,594 $2,214,718
Common Stock $2,776,717 $2,743,440 $2,574,594 $2,214,718
Employee Benefits $10,655,789 $10,899,814 $7,111,254 $3,959,871
Non Current Deferred Revenue $2,882,708 $5,619,986 $0 -
Long Term Capital Lease Obligation $4,546,519 $5,424,026 $3,481,680 $2,776,717
Current Deferred Revenue $103,163,711 $104,827,522 $170,079 $723,450
Current Capital Lease Obligation $1,050,050 $1,264,497 $828,208 $675,384
Current Accrued Expenses $9,942,198 $14,910,216 $13,664,206 $11,606,010
Investments And Advances $719,753 $511,468 $444,916 $444,916
Net PPE $8,045,453 $9,968,080 $8,484,206 $8,709,745
Accumulated Depreciation $-16,904,325 $-15,366,224 $-13,552,053 $-11,514,808
Gross PPE $24,949,779 $25,334,304 $22,036,260 $20,224,554
Leases $2,329,336 $2,296,060 $2,048,337 $2,021,223
Other Properties $13,476,874 $12,985,125 $12,611,692 $12,034,904
Machinery Furniture Equipment $3,635,736 $3,496,469 $3,129,198 $2,827,247
Buildings And Improvements $5,507,832 $6,556,650 $4,247,033 $3,337,483
Properties $0 $0 $0 $0
Other Short Term Investments $79,637,416 $159,250,182 $30,261,651 $112,153,223
Construction In Progress - $0 $0 $3,697
Fetched: 2026-06-24
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-86,471,367 $80,437,277 $-75,437,216 $-92,196,112
Operating Activities
Operating Cash Flow $-85,362,160 $81,147,170 $-74,450,021 $-90,669,102
Cash Flow From Continuing Operating Activities $-85,362,160 $81,147,170 $-74,450,021 $-90,669,102
Operating Gains Losses $-1,930,021 $-12,325 $1,094,418 $666,757
Investing Activities
Capital Expenditure $-1,109,208 $-709,893 $-987,195 $-1,527,009
Investing Cash Flow $78,312,529 $-129,764,976 $80,904,377 $29,286,781
Cash Flow From Continuing Investing Activities $78,312,529 $-129,764,976 $80,904,377 $29,286,781
Net Other Investing Changes $-209,517 $-66,552 - $2,465
Financing Activities
Issuance Of Capital Stock $7,395 $136,802 $53,978,976 $8,627
Financing Cash Flow $-1,257,102 $-1,380,347 $53,303,592 $-1,658,882
Cash Flow From Continuing Financing Activities $-1,257,102 $-1,380,347 $53,303,592 $-1,658,882
Net Common Stock Issuance $7,395 $136,802 $53,978,976 $-1,232
Common Stock Issuance $7,395 $136,802 $53,978,976 $8,627
Net Other Financing Charges - $-675,384 - $-956,384
Repurchase Of Capital Stock - - - $-9,860
Other
Repayment Of Debt $-1,264,497 $-841,765 $-675,384 $-701,266
End Cash Position $33,023,578 $44,707,233 $96,740,166 $38,928,260
Beginning Cash Position $44,707,233 $96,740,166 $38,928,260 $101,327,356
Effect Of Exchange Rate Changes $-3,376,921 $-2,034,780 $-1,946,043 $642,108
Changes In Cash $-8,306,733 $-49,998,153 $59,757,949 $-63,041,203
Net Issuance Payments Of Debt $-1,264,497 $-841,765 $-675,384 $-701,266
Net Long Term Debt Issuance $-1,264,497 $-841,765 $-675,384 $-701,266
Long Term Debt Payments $-1,264,497 $-841,765 $-675,384 $-701,266
Net Investment Purchase And Sale $79,612,766 $-128,988,531 $81,891,572 $30,811,325
Net PPE Purchase And Sale $-1,090,721 $-709,893 $-987,195 $-1,527,009
Sale Of PPE $18,487 $0 $0 $0
Purchase Of PPE $-1,109,208 $-709,893 $-987,195 $-1,527,009
Interest Received Cfo $2,337,963 $1,926,324 $733,310 $85,039
Interest Paid Cfo $-232,934 $-158,986 $-216,912 $-589,113
Change In Working Capital $-8,349,869 $132,505,952 $-18,683,987 $-10,392,044
Change In Other Working Capital $-4,401,090 $110,277,430 $-553,371 $-160,219
Change In Payables And Accrued Expense $-5,488,113 $2,896,265 $2,350,288 $-8,857,640
Change In Accrued Expense $-4,758,501 $1,692,158 $1,401,299 $-7,535,218
Change In Payable $-729,612 $1,204,107 $948,989 $-1,322,422
Change In Prepaid Assets $406,709 $2,631,287 $-2,154,328 $-2,117,354
Change In Receivables $1,132,624 $16,700,971 $-18,326,576 $743,169
Changes In Account Receivables $0 $18,240,304 $-18,240,304 $0
Other Non Cash Items $1,132,624 $231,701 $1,353,233 $-251,420
Stock Based Compensation $5,417,863 $6,741,518 $5,379,657 $4,104,068
Depreciation Amortization Depletion $3,084,830 $2,664,563 $2,729,883 $2,907,357
Depreciation And Amortization $3,084,830 $2,664,563 $2,729,883 $2,907,357
Depreciation $3,084,830 $2,664,563 $2,729,883 $2,907,357
Pension And Employee Benefit Expense $-1,911,535 $-12,325 $1,094,418 $666,757
Gain Loss On Sale Of PPE $-18,487 $0 $0 $0
Net Income From Continuing Operations $-86,822,616 $-62,751,577 $-66,839,624 $-87,199,747
Issuance Of Debt - - $0 $0
Long Term Debt Issuance - - $0 $0
Proceeds From Stock Option Exercised - - - $8,627
Common Stock Payments - - - $-9,860
Net Short Term Debt Issuance - - - $0
Short Term Debt Payments - - - $0
Fetched: 2026-06-24