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ACIU

AC Immune SA

Price Chart
Latest Quote

$2.25

-0.06 (-2.60%)
Current Price
Previous Close $2.31
Open $2.31
Day High $2.36
Day Low $2.03
Volume 469,024
Fetched: 2026-10-28T07:54:55
Stock Information
Note: Financial values converted from CHF to USD
Shares Outstanding 99.43M
Total Debt $4.94M
Cash Equivalents $90.77M
Revenue $21.09M
Net Income $-51.98M
Sector Healthcare
Industry Biotechnology
Market Cap $223.71M
EPS (TTM) $-0.54
Exchange NGM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$152.46M
Sales$21.09M
Income$-51.98M
Book/sh$0.43
Cash/sh$0.76
Employees90
Financial Ratios
Quick Ratio0.89
Current Ratio0.93
Debt/Eq11.66
Returns & Margins
ROA-16.04%
ROE-78.53%
Gross Margin-162.23%
Operating Margin7.89%
Profit Margin-246.48%
Ownership
Insider Ownership38.09%
Institutional Ownership24.34%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E3.74
P/S12.78
P/B5.24
Analyst Data
Recommendationnone
Target Price$8.57
Technical Indicators
SMA20$2.50
SMA50$2.63
SMA200$2.75
RSI26.47
ATR0.1060
Shares Float39.18M
Short Float7.59%
Short Ratio21.42
Volatility1.55
Rel Volume2.25
Performance History
Week-9.64%
Month-13.79%
Quarter-0.88%
6 Months-25.74%
YTD-33.04%
Year-30.77%
3 Years-8.54%
5 Years-62.75%
10 Years-84.55%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-10-27 $2.25 469,000
2026-10-26 $2.31 397,900
2026-10-23 $2.42 139,500
2026-10-22 $2.50 73,000
2026-10-21 $2.47 89,000
2026-10-20 $2.49 140,100
2026-10-19 $2.43 88,800
2026-10-16 $2.39 126,800
2026-10-15 $2.45 86,900
2026-10-14 $2.40 209,700
2026-10-13 $2.40 194,900
2026-10-12 $2.45 148,500
2026-10-09 $2.50 271,300
2026-10-08 $2.55 231,900
2026-10-07 $2.57 125,100
2026-10-06 $2.52 277,800
2026-10-05 $2.71 221,400
2026-10-02 $2.72 320,200
2026-10-01 $2.81 352,700
2026-09-30 $2.62 199,600
2026-09-29 $2.60 134,200
2026-09-28 $2.61 188,900
About AC Immune SA

AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $4,298,036 $32,850,561 $17,804,429 $4,733,493
Operating Revenue $4,298,036 $32,850,561 $17,804,429 $4,733,493
Expenses
Interest Expense $229,758 $159,988 $211,714 $427,037
Total Expenses $87,134,764 $95,857,142 $82,309,849 $89,956,816
Other Income Expense $-3,919,116 $-1,922,267 $-1,764,685 $472,748
Net Non Operating Interest Income Expense $2,013,689 $3,684,546 $1,044,135 $-344,035
Interest Expense Non Operating $229,758 $159,988 $211,714 $427,037
Operating Expense $87,134,764 $95,857,142 $82,309,849 $89,956,816
Other Operating Expenses $3,285,176 $5,449,231 $2,612,744 $5,851,006
General And Administrative Expense $14,016,432 $13,754,195 $12,722,089 $11,526,386
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Net Interest Income $2,013,689 $3,684,546 $1,044,135 $-344,035
Interest Income $2,243,447 $3,844,535 $1,255,849 $83,002
Normalized Income $-80,823,039 $-59,489,036 $-63,623,312 $-85,521,539
Net Income From Continuing And Discontinued Operation $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Total Operating Income As Reported $-83,384,057 $-63,006,580 $-64,505,420 $-85,223,323
Net Income Common Stockholders $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Net Income $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Net Income Including Noncontrolling Interests $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Net Income Continuous Operations $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Pretax Income $-84,742,155 $-61,244,302 $-65,225,969 $-85,094,610
Special Income Charges $-547,329 $0 $0 -
Interest Income Non Operating $2,243,447 $3,844,535 $1,255,849 $83,002
Operating Income $-82,836,728 $-63,006,580 $-64,505,420 $-85,223,323
Depreciation Amortization Depletion Income Statement $1,945,123 $1,386,968 $1,288,328 -
Depreciation And Amortization In Income Statement $1,945,123 $1,386,968 $1,288,328 -
Depreciation Income Statement $1,945,123 $1,386,968 $1,288,328 -
Per Share
Diluted EPS $-0.84 $-0.61 $-0.77 $-1.02
Basic EPS $-0.84 $-0.61 $-0.77 $-1.02
Other
Tax Effect Of Unusual Items $0 $-163,393 $-149,998 $61,457
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-77,582,371 $-56,561,331 $-60,585,101 $-82,302,631
Total Unusual Items $-3,919,116 $-1,922,267 $-1,764,685 $472,748
Total Unusual Items Excluding Goodwill $-3,919,116 $-1,922,267 $-1,764,685 $472,748
Reconciled Depreciation $3,010,911 $2,600,715 $2,664,469 $2,837,690
EBITDA (Bullshit earnings) $-81,501,486 $-58,483,599 $-62,349,786 $-81,829,884
EBIT $-84,512,397 $-61,084,313 $-65,014,255 $-84,667,573
Diluted Average Shares $121,196,312 $120,093,942 $101,880,907 $100,509,332
Basic Average Shares $121,196,312 $120,093,942 $101,880,907 $100,509,332
Diluted NI Availto Com Stockholders $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Tax Provision $0 $3,609 $12,029 $15,638
Restructuring And Mergern Acquisition $547,329 $0 $0 -
Gain On Sale Of Security $-3,371,787 $-1,922,267 $-1,764,685 $472,748
Research And Development $67,888,033 $75,266,748 $65,686,688 $72,579,423
Selling General And Administration $14,016,432 $13,754,195 $12,722,089 $11,526,386
Salaries And Wages $14,016,432 $13,754,195 $12,722,089 $11,526,386
Fetched: 2026-10-15
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $-6,654,557 $74,405,457 $132,594,340 $142,636,322
Total Assets $185,551,721 $277,770,028 $219,910,745 $223,668,669
Total Non Current Assets $69,202,825 $70,874,885 $69,361,610 $69,581,745
Other Non Current Assets $1,203 - - -
Investmentin Financial Assets $702,506 $499,212 $434,254 $434,254
Goodwill And Other Intangible Assets $60,646,450 $60,646,450 $60,646,450 $60,646,450
Other Intangible Assets $60,646,450 $60,646,450 $60,646,450 $60,646,450
Current Assets $116,348,896 $206,895,143 $150,549,134 $154,086,924
Prepaid Assets $4,778,001 $5,174,965 $7,743,201 $5,663,351
Receivables $1,609,508 $2,650,034 $18,847,362 $962,337
Other Receivables $529,285 $1,495,230 $350,050 $639,954
Taxes Receivable $1,080,223 $1,154,804 $694,085 $322,383
Cash Cash Equivalents And Short Term Investments $109,961,387 $199,070,144 $123,958,572 $147,461,237
Cash And Cash Equivalents $32,232,260 $43,635,948 $94,422,057 $37,995,453
Accounts Receivable - $0 $17,803,226 $0
Debt
Total Debt $5,462,463 $6,528,251 $4,206,614 $3,369,381
Long Term Debt And Capital Lease Obligation $4,437,574 $5,294,054 $3,398,251 $2,710,180
Current Debt And Capital Lease Obligation $1,024,888 $1,234,197 $808,363 $659,201
Liabilities
Total Liabilities Net Minority Interest $131,559,828 $142,718,121 $26,669,955 $20,385,897
Total Non Current Liabilities Net Minority Interest $17,651,658 $21,418,003 $10,339,103 $6,575,165
Non Current Deferred Liabilities $2,813,632 $5,485,318 $0 -
Current Liabilities $113,908,170 $121,300,118 $16,330,851 $13,810,733
Current Deferred Liabilities $100,691,680 $102,315,623 $166,003 $706,114
Payables And Accrued Expenses $12,191,601 $17,750,298 $15,356,486 $12,445,418
Payables $2,487,640 $3,197,363 $2,019,704 $1,117,513
Accounts Payable $2,487,640 $3,197,363 $2,019,704 $1,117,513
Equity
Common Stock Equity $53,991,893 $135,051,907 $193,240,790 $203,282,772
Total Equity Gross Minority Interest $53,991,893 $135,051,907 $193,240,790 $203,282,772
Stockholders Equity $53,991,893 $135,051,907 $193,240,790 $203,282,772
Gains Losses Not Affecting Retained Earnings $8,420 $-6,015 $-61,349 $12,029
Retained Earnings $-528,107,449 $-442,962,316 $-380,359,917 $-317,589,109
Other
Treasury Shares Number $13,111,563 $13,111,563 $6,308,066 $7,474,974
Ordinary Shares Number $122,387,836 $120,785,721 $119,327,122 $100,588,667
Share Issued $135,499,398 $133,897,284 $125,635,188 $108,063,641
Tangible Book Value $-6,654,557 $74,405,457 $132,594,340 $142,636,322
Invested Capital $53,991,893 $135,051,907 $193,240,790 $203,282,772
Working Capital $2,440,726 $85,595,025 $134,218,283 $140,276,192
Capital Lease Obligations $5,462,463 $6,528,251 $4,206,614 $3,369,381
Total Capitalization $53,991,893 $135,051,907 $193,240,790 $203,282,772
Foreign Currency Translation Adjustments $8,420 $-6,015 $-61,349 $12,029
Treasury Stock $262,237 $262,237 $126,307 $149,162
Additional Paid In Capital $579,642,977 $575,604,772 $571,275,461 $518,847,365
Capital Stock $2,710,180 $2,677,701 $2,512,901 $2,161,648
Common Stock $2,710,180 $2,677,701 $2,512,901 $2,161,648
Employee Benefits $10,400,452 $10,638,631 $6,940,852 $3,864,984
Non Current Deferred Revenue $2,813,632 $5,485,318 $0 -
Long Term Capital Lease Obligation $4,437,574 $5,294,054 $3,398,251 $2,710,180
Current Deferred Revenue $100,691,680 $102,315,623 $166,003 $706,114
Current Capital Lease Obligation $1,024,888 $1,234,197 $808,363 $659,201
Current Accrued Expenses $9,703,961 $14,552,935 $13,336,782 $11,327,904
Investments And Advances $702,506 $499,212 $434,254 $434,254
Net PPE $7,852,666 $9,729,223 $8,280,906 $8,501,041
Accumulated Depreciation $-16,499,260 $-14,998,015 $-13,227,316 $-11,238,888
Gross PPE $24,351,927 $24,727,238 $21,508,222 $19,739,929
Leases $2,273,520 $2,241,041 $1,999,254 $1,972,790
Other Properties $13,153,938 $12,673,972 $12,309,488 $11,746,521
Machinery Furniture Equipment $3,548,616 $3,412,686 $3,054,216 $2,759,500
Buildings And Improvements $5,375,853 $6,399,538 $4,145,265 $3,257,509
Properties $0 $0 $0 $0
Other Short Term Investments $77,729,127 $155,434,195 $29,536,515 $109,465,784
Construction In Progress - $0 $0 $3,609
Fetched: 2026-10-15
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-84,399,322 $78,509,822 $-73,629,573 $-89,986,889
Operating Activities
Operating Cash Flow $-83,316,694 $79,202,705 $-72,666,034 $-88,496,470
Cash Flow From Continuing Operating Activities $-83,316,694 $79,202,705 $-72,666,034 $-88,496,470
Operating Gains Losses $-1,883,774 $-12,029 $1,068,194 $650,780
Investing Activities
Capital Expenditure $-1,082,629 $-692,882 $-963,539 $-1,490,419
Investing Cash Flow $76,435,987 $-126,655,521 $78,965,729 $28,585,005
Cash Flow From Continuing Investing Activities $76,435,987 $-126,655,521 $78,965,729 $28,585,005
Net Other Investing Changes $-204,497 $-64,958 - $2,406
Financing Activities
Issuance Of Capital Stock $7,218 $133,524 $52,685,521 $8,420
Financing Cash Flow $-1,226,979 $-1,347,271 $52,026,320 $-1,619,131
Cash Flow From Continuing Financing Activities $-1,226,979 $-1,347,271 $52,026,320 $-1,619,131
Net Common Stock Issuance $7,218 $133,524 $52,685,521 $-1,203
Common Stock Issuance $7,218 $133,524 $52,685,521 $8,420
Net Other Financing Charges - $-659,201 - $-933,466
Repurchase Of Capital Stock - - - $-9,623
Other
Repayment Of Debt $-1,234,197 $-821,595 $-659,201 $-684,462
End Cash Position $32,232,260 $43,635,948 $94,422,057 $37,995,453
Beginning Cash Position $43,635,948 $94,422,057 $37,995,453 $98,899,328
Effect Of Exchange Rate Changes $-3,296,003 $-1,986,022 $-1,899,412 $626,722
Changes In Cash $-8,107,686 $-48,800,087 $58,326,016 $-61,530,597
Net Issuance Payments Of Debt $-1,234,197 $-821,595 $-659,201 $-684,462
Net Long Term Debt Issuance $-1,234,197 $-821,595 $-659,201 $-684,462
Long Term Debt Payments $-1,234,197 $-821,595 $-659,201 $-684,462
Net Investment Purchase And Sale $77,705,068 $-125,897,680 $79,929,269 $30,073,018
Net PPE Purchase And Sale $-1,064,585 $-692,882 $-963,539 $-1,490,419
Sale Of PPE $18,044 $0 $0 $0
Purchase Of PPE $-1,082,629 $-692,882 $-963,539 $-1,490,419
Interest Received Cfo $2,281,941 $1,880,165 $715,738 $83,002
Interest Paid Cfo $-227,352 $-155,177 $-211,714 $-574,996
Change In Working Capital $-8,149,788 $129,330,816 $-18,236,278 $-10,143,027
Change In Other Working Capital $-4,295,630 $107,634,938 $-540,111 $-156,380
Change In Payables And Accrued Expense $-5,356,606 $2,826,864 $2,293,970 $-8,645,391
Change In Accrued Expense $-4,644,477 $1,651,610 $1,367,721 $-7,354,657
Change In Payable $-712,129 $1,175,254 $926,249 $-1,290,734
Change In Prepaid Assets $396,964 $2,568,236 $-2,102,705 $-2,066,618
Change In Receivables $1,105,484 $16,300,778 $-17,887,431 $725,361
Changes In Account Receivables $0 $17,803,226 $-17,803,226 $0
Other Non Cash Items $1,105,484 $226,149 $1,320,807 $-245,396
Stock Based Compensation $5,288,039 $6,579,976 $5,250,749 $4,005,726
Depreciation Amortization Depletion $3,010,911 $2,600,715 $2,664,469 $2,837,690
Depreciation And Amortization $3,010,911 $2,600,715 $2,664,469 $2,837,690
Depreciation $3,010,911 $2,600,715 $2,664,469 $2,837,690
Pension And Employee Benefit Expense $-1,865,730 $-12,029 $1,068,194 $650,780
Gain Loss On Sale Of PPE $-18,044 $0 $0 $0
Net Income From Continuing Operations $-84,742,155 $-61,247,910 $-65,237,998 $-85,110,248
Issuance Of Debt - - $0 $0
Long Term Debt Issuance - - $0 $0
Proceeds From Stock Option Exercised - - - $8,420
Common Stock Payments - - - $-9,623
Net Short Term Debt Issuance - - - $0
Short Term Debt Payments - - - $0
Fetched: 2026-10-15